Reports in the literature of infection of the central nervous system with Bacillus cereus
| Study | Sex/Gestation/ Weight | Age at Onset | Predisposing Factors | Nature of Infection | Treatment | Outcome |
|---|---|---|---|---|---|---|
| Leffert et al, 1970 | Not reported | 18 wk | Dandy-Walker cyst, ventricular shunt | Meningitis | Ampicillin, gentamicin, shunt removal | No sequelae |
| Raphael and Donaghue, 1976 | Not reported | 8 mo | Ventricular shunt | Meningitis | Ampicillin, gentamicin, shunt removal | No sequelae |
| Turnbull et al, 1977 | Female/32 wk/1320 g | 4 d | Necrotizing enterocolitis, cerebral hemorrhage | Meningitis | Ampicillin, gentamicin | Died |
| Hendrickx et al, 1981 (12) | Female/32 wk | 8 d | Respiratory distress syndrome, central line | Meningitis | Ampicillin, gentamicin, erythromycin | Died |
| Feder et al, 1988 | Female/32 wk/1500 g | 7 wk | Infected intravenous catheter | Meningitis | Chloramphenicol | Cerebral palsy |
| Patrick et al, 1989 | Female/26 wk/830 g | 7 d | Bilateral thalamic hemorrhage | Encephalitis | Vancomycin, amikacin | Died |
| Weisse et al, 1991 | Male erm/3700 g | 3 wk | None | Meningitis | Gentamicin, chloramphenicol | No sequelae |
| Weisse et al, 1991 | Male/36 wk/2710 g | 5 d | Myelomeningocoele sac ruptured | Meningitis | Vancomycin | No sequelae |
| Chu et al, 1997 | Male/26 wk/1500 g | 4 wk | Bronchopulmonary dysplasia, dexamethasone used | Meningitis | Vancomycin, amikacin | Died |
| Present report, case 1 | Female/31 wk/1500 g | 5 d | None | Meningo-encephalitis | Amoxilline/clafuran vancomycin, amikacin | Died |
| Present report, case 2 | Female/29 wk/976 g | 5 d | Respiratory distress syndrome | Meningo-encephalitis | Vancomycin, amikacin | Died |
| Present report, case 3 | Female/34 wk/1565 g | 13 d | Duodenal atresia, malrotation, central line | Meningo-encephalitis Ventriculitis | Amoxilline/clafuran vancomycin, clindamycin | Died |