Characteristics of patients with and without hemorrhagic transformation after IA reperfusion therapy
| Hemorrhagic Transformation | No Hemorrhagic Transformation | P Value | |
|---|---|---|---|
| Patient demographics | |||
| Number of cases | 13 | 19 | |
| Mean age (years) | 65.2 | 67.9 | .63 |
| Female (%) | 46.2% | 52.6% | .99 |
| Clinical characteristics | |||
| Left-hemispheric MCA lesions (%) | 33.3% | 38.5% | .20 |
| Mean initial NIHSS score | 19.9 | 17.6 | .20 |
| Mean initial serum glucose (mg/dl) | 186 | 173 | .63 |
| Patients on antithrombotics (%) | 53.8% | 42.1% | .99 |
| Treatment characteristics | |||
| Mean time from symptoms to initial image (hours) | 2.04 | 1.77 | .56 |
| Mean time from symptoms to treatment (hours) | 4.33 | 4.22 | .80 |
| Mean time from treatment to recanalization (hours) | 0.92 | 0.95 | .92 |
| Patients with recanalization <6 h after onset (%) | 69.2% | 57.9% | .71 |
| Patients receiving GP-IIbIIIa inhibitors (%) | 54.0% | 52.9% | .99 |
| Patients receiving IV tPA (%) | 15.4% | 15.8% | 1.0 |
| Mean dose IA tPA (all patients) (mg) | 13.7 | 10.9 | .31 |
| Mean total dose tPA (IV + IA patients) (mg) | 24.5 | 22.9 | .87 |
Note.—GP indicates glycoprotein; IA, intraarterial; IV, intravenous; MCA, middle cerebral artery; NIHSS, National Institutes of Health Stroke Scale; tPA, tissue plasminogen activator.