Age-dependent diffusion changes for the study subjects
| Location | Dav (10−5 cm2/second) | R |
|---|---|---|
| Thalamus | Dav = 0.239 exp(−4.072 × age) + 0.0123 exp(−0.0821 × age) + 0.724 | 0.920 |
| PVWM | Dav = 0.527 exp(−2.301 × age) + 0.212 exp(−0.221 × age) + 0.771 | 0.942 |
| Whole brain (BDav) | BDav = 0.251 exp(−1.139 × age) + 0.157 exp(−0.102 × age) + 0.732 | 0.959 |
| Caudate | Dav = 0.241 exp(−1.583 × age) + 0.201 exp(−0.243 × age) + 0.704 | 0.921 |
| Corpus callosum | ||
| Genu* | Dav = 0.431 exp(−0.608 × age) + 0.748 | 0.912 |
| Splenium | Dav = 0.398 exp(−1.490 × age) + 0.061 exp(−0.0209 × age) + 0.743 | 0.929 |
Note.—Subjects’ age range was 0.01–17 years.
* Single exponential decay describes the age dependency of diffusion changes in the genu of the corpus callosum.