Baseline clinical characteristics in R and NR groups
| Characteristics | R Group (n=72) | NR Group (n=116) | P Value |
|---|---|---|---|
| Age, years | 65 [56, 71] | 65 [56, 72] | .47 |
| Sex, female | 47 (65) | 89 (77) | .10 |
| Medical history | |||
| Hypertension | 46 (64) | 52 (45) | .02b |
| Diabetes mellitus | 4 (5.6) | 9 (7.8) | .77 |
| Hyperlipidemia | 14 19) | 27 (23) | .59 |
| Polycystic kidney disease | 1 (1.4) | 4 (3.4) | .65 |
| Prior stroke | 4 (5.6) | 2 (1.7) | .21 |
| Cerebral small vessel diseasea | 39 (54) | 50 (43) | .18 |
| Smoking | |||
| Current | 10 (14) | 18 (16) | .46 |
| Past smoker | 18 (25) | 20 (17) | |
| None | 44 (61) | 78 (67) | |
| Drinking | 15 (21) | 18 (16) | .43 |
| Family history | |||
| Cerebral aneurysm | 10 (14) | 24 (21) | .33 |
| Polycystic kidney | 1 (1.4) | 1 (0.9) | 1 |
| Aneurysm characteristics | |||
| Thrombosed aneurysm | 6 (8.3) | 5 (4.3) | .34 |
| Multiple aneurysms | 26 (36) | 43 (37) | 1 |
| Aneurysm location | |||
| ACA/ACoA | 10 (14) | 17 15) | .13 |
| MCA | 9 (13) | 18 (16) | |
| ICA | 37 (51) | 65 (56) | |
| PCA | 0 (0) | 1 (0.9) | |
| BA/SCA | 16 (22) | 11 (9.5) | |
| VA/PICA | 0 (0) | 4 (3.4) | |
| Posterior circulation | 15 (21) | 16 (14) | .23 |
Note:—ACA indicates anterior cerebral artery; ACoA, anterior communicating artery; BA, basilar artery; NR, non-major re-recanalization; PCA, posterior cerebral artery; R, major re-recanalization; SCA, superior cerebellar artery; VA, vertebral artery.
a Cerebral small vessel disease was diagnosed if 1 or more of the following radiologic features were seen on MRI: 1) subcortical small, focal infarction, 2) diffuse white matter lesions present as white matter hyperintensities on T2WI, 3) microbleeding in the subcortical region.
b P < .05. Unless otherwise indicated, values represent the number of aneurysms (%) or median (IQR). Not all percentage totals reach 100% because of rounding.