Table 5:

Hazard ratios, confidence intervals, and P values of AI-VTRA, age, sex, primary self-reported race, self-reported ethnicity, and IDH

Variable	Level	HR [95% CI]	P Value
AI-VTRA	2 – No change	REF^{^a}	REF^{^a}
	1 – Improve	1.26 [0.86, 1.87]	.24
	3 – Worsening	1.20 [0.81, 1.77]	.36
	4 – RANO progression	1.54 [1.07, 2.21]	.02
Age		1.11 [0.95, 1.30]	.18
Sex	Female	REF^{^a}	REF^{^a}
	Male	1.25 [0.95, 1.65]	.11
Primary self-reported race	White	REF^{^a}	REF^{^a}
	Black or African American	1.02 [0.61, 1.71]	.95
	Asian	0.45 [0.11, 1.94]	.28
	American Indian or Alaskan Native	1.29 [0.15, 11.12]	.82
	Not reported/declined	2.04 [0.51, 8.20]	.32
	Other	1.34 [0.27, 6.56]	.72
Self-reported ethnicity	Hispanic/Latino	REF^{^a}	REF^{^a}
	Not Hispanic/Latino	1.27 [0.59, 2.72]	.54
	Not reported/declined	N/A	N/A
IDH	Negative (wild-type)	REF^{^a}	REF^{^a}
	Positive (mutant)	0.68 [0.31, 1.51]	.34