The distribution of the severity of white matter hyperintensities for aICSL and aICSR groups. The total Fazekas score is the summation of scores for periventricular white matter and deep white matter
| HC (n = 15) | aICSL (n = 22) | aICSR (n = 33) | P Value | ||||
|---|---|---|---|---|---|---|---|
| aICSL vs HC | aICSR vs HC | aICSL vs aICSR | |||||
| Fazekas score for periventricular white matter | .501 | .586 | .637 | ||||
| 0 | 1 (6.7%) | 3 (13.6%) | 4 (12.1%) | ||||
| 1 | 11 (73.3%) | 9 (50.0%) | 19 (60.6%) | ||||
| 2 | 3 (20.0%) | 6 (31.8%) | 6 (18.2%) | ||||
| 3 | 0 (0.0%) | 1 (4.5%) | 3 (9.1%) | ||||
| Fazekas score for deep white matter | .705 | .693 | .693 | ||||
| 0 | 3 (20.0%) | 3 (13.6%) | 6 (18.2%) | ||||
| 1 | 10 (66.7%) | 10 (59.1%) | 20 (60.6%) | ||||
| 2 | 2 (13.3%) | 5 (22.7%) | 3 (12.1%) | ||||
| 3 | 0 (0.0%) | 1 (4.5%) | 3 (9.1%) | ||||
| Total Fazekas score | .413 | .801 | .157 | ||||
| 0 | 1 (6.7%) | 3 (13.6%) | 1 (3.0%) | ||||
| 1 | 2 (13.3%) | 0 (0.0%) | 8 (24.2%) | ||||
| 2 | 8 (53.3%) | 8 (45.5%) | 14 (42.4%) | ||||
| 3 | 3 (20.0%) | 3 (18.2%) | 3 (12.1%) | ||||
| 4 | 1 (6.7%) | 4 (18.2%) | 3 (9.1%) | ||||
| 5 | 0 (0.0%) | 0 (0.0%) | 1 (3.0%) | ||||
| 6 | 0 (0.0%) | 1 (4.5%) | 2 (6.1%) | ||||
Note:—T2 FLAIR images are not available in 10 HCs, 3 aICSL and 1 aICSR patients. The Fazekas scores for those cases were assessed with diffusion tensor imaging.