Associations of pulsatility with brain MR imaging findingsa
| Pulsatility in PXE | ||
|---|---|---|
| Age and Sex-Adjusted (n = 50) | Multivariable-Adjusted (n = 50) | |
| MR imaging volumes (β [95% CI]) | ||
| GM (mL) | 3.8 [–73.9–81.6] | 7.4 [–71.4–86.1] |
| WM (mL) | 22.7 [–55.8–101.3] | 23.1 [–57.0–103.2] |
| CSF (mL) | 68.6 [–115.5–252.7] | 45.6 [–131.8–223.0] |
| Cortical thickness (µm) | 29.5 [–145.0–204.1] | 31.9 [–146.0–209.7] |
| WML (mL) | 26.5 [11.6–41.3]c | 25.9 [10.8–40.9]c |
| Brain infarctions (RR [95%CI]) | ||
| Lacunar infarctions | 1.7 [0.1–23.6] | 1.8 [0.1–25.0] |
| All infarctions | 2.3 [0.2–1.2] | 2.5 [0.2–33.6] |
a For pulsatility, MR imaging volumes and infarctions are adjusted for age and sex (model 1) and age, sex, and hypertension (model 2). P < .05 was statistically significant.
b P < .05.
c P < .01.