Relative volume change per week based on linear regression analysesa
| Structure | Initial Relative Volume | Final Relative Volume | Change in Relative Volume per Week (95% CI) | P Value |
|---|---|---|---|---|
| Intraventricular CSF | 23.52% (20.912%–26.12%) | 8.64% (7.45%–9.84%) | −2.12 (−2.58 to −1.66) | .001 |
| Supratentorial parenchyma | 38.06% (34.25%–41.87%) | 48.15% (46.39%–49.90%) | 1.44 (0.77–2.11) | .001 |
| Extra-axial CSF | 32.26% (27.65%–36.86%) | 39.62% (37.50%–41.74%) | 1.05 (0.24–1.87) | .02 |
| Brainstem | 3.57% (2.97%–4.18%) | 1.93% (1.66%–2.21%) | −0.23 (−0.34 to −0.13) | .001 |
| Cerebellum | 2.57% (2.16%–2.98%) | 1.63% (1.44%–1.8%2) | −0.13 (−0.21 to −0.06) | .001 |
↵a Relative volume is expressed in terms of percentage. Data in parentheses are 95% CIs. ROIs are sorted in descending order based on the magnitude of the change of relative volume. The initial relative volume represents an estimate of 12 weeks' GA, and the final relative volume represents an estimate of 19 weeks' GA.