Summary of the obtained LME models describing ADC and ΔADC before lesion detection on FLAIR-weighted images
| Predictors | ADC before Detection | ΔADC before Detection | ||||
|---|---|---|---|---|---|---|
| Estimates | 95% CI | P | Estimates | 95% CI | P | |
| (Intercept) | 834 | 806–861 | <.01 | 83.2 | 59.9–106.5 | <.01 |
| Time (mo) | 0.44 | −0.17–1.04 | .15 | 0.57 | 0.01–1.14 | .047 |
| Male sex | 35.4 | −3.6–74.5 | .08 | 10.7 | −21.8–43.1 | .52 |
| Age (baseline, mean centered) (yr) | 1.0 | −0.8–2.8 | .25 | 0.32 | −1.22–1.86 | .68 |
| Time:male sex | −0.16 | −1.10–0.79 | .74 | 0.11 | −0.71–0.94 | .79 |
| Time:age | −0.00 | −0.05–0.05 | .85 | −0.00 | −0.05–0.04 | .87 |
| Observations | 233 | 225 | ||||
| Marginal R2 | 0.114 | 0.035 | ||||
| Conditional R2 | 0.601 | 0.452 | ||||