RT Journal Article
SR Electronic
T1 Evaluation of the Prevalence of Punctate White Matter Lesions in a Healthy Volunteer Neonatal Population
JF American Journal of Neuroradiology
JO Am. J. Neuroradiol.
FD American Society of Neuroradiology
SP 1210
OP 1213
DO 10.3174/ajnr.A7578
VO 43
IS 8
A1 Kular, S.
A1 Holmes, H.
A1 Hart, A.
A1 Griffiths, P.
A1 Connolly, D.
YR 2022
UL http://www.ajnr.org/content/43/8/1210.abstract
AB SUMMARY: Hypoxic-ischemic injury is the most common cause of neonatal encephalopathy. T1-weighted punctate white matter lesions have been described in hypoxic-ischemic injury. We have reviewed a healthy volunteer neonatal population to assess the prevalence of punctate white matter lesions in neonates with no clinical signs of hypoxic-ischemic injury. Fifty-two subjects were scanned on a neonatal-specific 3T MR imaging scanner. Twelve patients were excluded due to the lack of T1-weighted imaging, leaving a total of 40 patients (35 term, 5 preterm) assessed in the study. One had a solitary T1-punctate white matter lesion. We concluded that solitary punctate white matter lesions have a low prevalence in healthy neonates.HIIhypoxic-ischemic injuryPWMLpunctate white matter lesionSDHsubdural hematoma