RT Journal Article SR Electronic T1 Influenza A Encephalopathy, Cerebral Vasculopathy, and Posterior Reversible Encephalopathy Syndrome: Combined Occurrence in a 3-Year-Old Child JF American Journal of Neuroradiology JO Am. J. Neuroradiol. FD American Society of Neuroradiology SP 1443 OP 1446 DO 10.3174/ajnr.A1903 VO 31 IS 8 A1 Bartynski, W.S. A1 Upadhyaya, A.R. A1 Petropoulou, K.A. A1 Boardman, J.F. YR 2010 UL http://www.ajnr.org/content/31/8/1443.abstract AB SUMMARY: Encephalopathy is an uncommon complication of childhood influenza infection, typically recognized during influenza epidemics. Imaging hallmarks include characteristic thalamic lesions, thalamic necrosis and hemispheric edema. We describe a child with acute influenza A associated necrotizing encephalopathy with MR angiographic evidence of significant cerebral vasculopathy and a hemispheric edema pattern consistent with PRES. This case reinforces that significant cerebral vasculopathy can accompany influenza infection and that influenza is a likely trigger for PRES. ADEMacute disseminated encephalomyelitisANEacute necrotizing encephalopathyMIPmaximum intensity projectionPCAposterior cerebral arteryPCRpolymerase chain reactionPRESposterior reversible encephalopathy syndromeRBCred blood cell countTNFtumor necrosis factorWBCwhite blood cell count