RT Journal Article
SR Electronic
T1 Methadone-Induced Toxic Leukoencephalopathy: MR Imaging and MR Proton Spectroscopy Findings
JF American Journal of Neuroradiology
JO Am. J. Neuroradiol.
FD American Society of Neuroradiology
SP 565
OP 566
DO 10.3174/ajnr.A1889
VO 31
IS 3
A1 Salgado, R.A.
A1 Jorens, P.G.
A1 Baar, I.
A1 Cras, P.
A1 Hans, G.
A1 Parizel, P.M.
YR 2010
UL http://www.ajnr.org/content/31/3/565.abstract
AB SUMMARY: We report the clinical, MR imaging, and proton MR spectroscopy findings in a middle-aged woman with proved methadone-induced toxic leukoencephalopathy. The imaging characteristics of this unusual condition have been reported only rarely in the medical literature. We show that the imaging findings in methadone-induced toxic leukoencephalopathy are similar, though not identical, to previously reported cases of neurologic deterioration due to heroin inhalation. ChocholineCrcreatineFLAIRfluid-attenuated inversion recoveryNAAN-acetylaspartate