PT - JOURNAL ARTICLE AU - Horváthy-Szőcs, A. AU - Liptai, Z. AU - Dobner, S. AU - Rudas, G. AU - Barsi, P. TI - A Closer Investigation of the Synchronous Bilateral Pattern of MRI Lesions in Acute Necrotizing Encephalopathy Type 1 AID - 10.3174/ajnr.A7305 DP - 2021 Sep 30 TA - American Journal of Neuroradiology 4099 - http://www.ajnr.org/content/early/2021/09/30/ajnr.A7305.short 4100 - http://www.ajnr.org/content/early/2021/09/30/ajnr.A7305.full AB - SUMMARY: We observed a lesion pattern in a series of 4 cases of RANBP2-mutation–linked acute necrotizing encephalopathy, which appears to be specific for this condition. The setting of synchronous bilateral mammillary, amygdaloid, and lateral geniculate lesions, along with claustro-parahippocampal lesions, can serve as a diagnostic tool in this condition. We add several further details to the MR imaging features of the typical brain lesions encountered in this disease.ANE1acute necrotizing encephalopathy type 1RANBP2RAN binding protein 2