PT  - JOURNAL ARTICLE
AU  - Bartstra, J.W.
AU  - van Tuijl, R.J.
AU  - de Jong, P.A.
AU  - Mali, W.P.T.M.
AU  - van der Schaaf, I.C.
AU  - Ruigrok, Y.M.
AU  - Rinkel, G.J.E.
AU  - Velthuis, B.K.
AU  - Spiering, W.
AU  - Zwanenburg, J.J.M.
TI  - Pulsatility Attenuation along the Carotid Siphon in Pseudoxanthoma Elasticum
AID  - 10.3174/ajnr.A7288
DP  - 2021 Sep 23
TA  - American Journal of Neuroradiology
4099  - http://www.ajnr.org/content/early/2021/09/23/ajnr.A7288.short
4100  - http://www.ajnr.org/content/early/2021/09/23/ajnr.A7288.full
AB  - SUMMARY: We compared velocity pulsatility, distensibility, and pulsatility attenuation along the intracranial ICA and MCA between 50 patients with pseudoxanthoma elasticum and 40 controls. Patients with pseudoxanthoma elasticum had higher pulsatility and lower distensibility at all measured locations, except for a similar distensibility at C4. The pulsatility attenuation over the siphon was similar between patients with pseudoxanthoma elasticum and controls. This finding suggests that other disease mechanisms are the main contributors to increased intracranial pulsatility in pseudoxanthoma elasticum.PIpulsatility indexPXEpseudoxanthoma elasticumSVDsmall-vessel disease2D-PC2D phase-contrast