PT - JOURNAL ARTICLE AU - Miller, T.R. AU - Shivashankar, R. AU - Mossa-Basha, M. AU - Gandhi, D. TI - Reversible Cerebral Vasoconstriction Syndrome, Part 1: Epidemiology, Pathogenesis, and Clinical Course AID - 10.3174/ajnr.A4214 DP - 2015 Aug 01 TA - American Journal of Neuroradiology PG - 1392--1399 VI - 36 IP - 8 4099 - http://www.ajnr.org/content/36/8/1392.short 4100 - http://www.ajnr.org/content/36/8/1392.full SO - Am. J. Neuroradiol.2015 Aug 01; 36 AB - SUMMARY: Reversible cerebral vasoconstriction syndrome is a clinical and radiologic syndrome that represents a common presentation of a diverse group of disorders. The syndrome is characterized by thunderclap headache and reversible vasoconstriction of cerebral arteries, which can either be spontaneous or related to an exogenous trigger. The pathophysiology of reversible cerebral vasoconstriction syndrome is unknown, though alterations in cerebral vascular tone are thought to be a key underlying mechanism. The syndrome typically follows a benign course; however, reversible cerebral vasoconstriction syndrome may result in permanent disability or death in a small minority of patients secondary to complications such as ischemic stroke or intracranial hemorrhage.RCVSreversible cerebral vasoconstriction syndromePRESposterior reversible encephalopathy syndrome