PT  - JOURNAL ARTICLE
AU  - Gaur, P.
AU  - Dixon, L.
AU  - Jones, B.
AU  - Lyall, H.
AU  - Jan, W.
TI  - COVID-19-Associated Cytotoxic Lesions of the Corpus Callosum
AID  - 10.3174/ajnr.A6713
DP  - 2020 Aug 20
TA  - American Journal of Neuroradiology
4099  - http://www.ajnr.org/content/early/2020/08/20/ajnr.A6713.short
4100  - http://www.ajnr.org/content/early/2020/08/20/ajnr.A6713.full
AB  - SUMMARY: There are very limited published data on the neurologic complications associated with coronavirus disease 2019 (COVID-19) in the pediatric population. Here we present the first 2 pediatric cases of presumed COVID-19 related cytotoxic lesions of the corpus callosum. Similar to reports in adults, these cases suggest that the COVID-19 infection in children may rarely mediate a hyperinflammatory response that can cause CNS pathology. As the pandemic continues further, the presentation of cytotoxic lesions of the corpus callosum should prompt radiologists to consider COVID-19, among other known causes.CLOCCcytotoxic lesions of the corpus callosumCOVID-19coronavirus disease 2019CRPC-reactive proteinRT-PCRreal-time reverse transcriptase polymerase chain reactionSARS-CoV-2Severe Acute Respiratory Syndrome coronavirus 2