RT Journal Article SR Electronic T1 Validating the Automatic Independent Component Analysis of DSA JF American Journal of Neuroradiology JO Am. J. Neuroradiol. FD American Society of Neuroradiology SP 540 OP 542 DO 10.3174/ajnr.A5963 VO 40 IS 3 A1 Hong, J.-S. A1 Kao, Y.-H. A1 Chang, F.-C. A1 Lin, C.-J. YR 2019 UL http://www.ajnr.org/content/40/3/540.abstract AB SUMMARY: Time-density curve analysis of DSA provides useful blood flow information. However, manually selecting the ROI is time-consuming. We developed an automatic technique to provide arterial, capillary, and venous vasculatures with corresponding time-density curves. This study retrospectively analyzed the data of 36 patients with unilateral carotid stenosis. We found that the full width at half maximum of the time-density curve for the automatically segmented capillary vasculature is a suitable representation of the cerebral circulation time.CCTcerebral circulation timeFWHMfull width at half maximumI1 and I2the internal carotid artery at 2 locationsIAcervical internal carotid artery in the lateral viewIBcavernous segment of the internal carotid artery in the lateral viewMCPmanually selected capillary phasePAposteroanteriorTDCtime-density curve