RT Journal Article SR Electronic T1 Validating the Automatic Independent Component Analysis of DSA JF American Journal of Neuroradiology JO Am. J. Neuroradiol. FD American Society of Neuroradiology DO 10.3174/ajnr.A5963 A1 Hong, J.-S. A1 Kao, Y.-H. A1 Chang, F.-C. A1 Lin, C.-J. YR 2019 UL http://www.ajnr.org/content/early/2019/01/24/ajnr.A5963.abstract AB SUMMARY: Time-density curve analysis of DSA provides useful blood flow information. However, manually selecting the ROI is time-consuming. We developed an automatic technique to provide arterial, capillary, and venous vasculatures with corresponding time-density curves. This study retrospectively analyzed the data of 36 patients with unilateral carotid stenosis. We found that the full width at half maximum of the time-density curve for the automatically segmented capillary vasculature is a suitable representation of the cerebral circulation time.CCTcerebral circulation timeFWHMfull width at half maximumI1 and I2the internal carotid artery at 2 locationsIAcervical internal carotid artery in the lateral viewIBcavernous segment of the internal carotid artery in the lateral viewMCPmanually selected capillary phasePAposteroanteriorTDCtime-density curve