RT Journal Article
SR Electronic
T1 Progressive brain failure after diffuse hypoxic ischemic brain injury: a serial MR and proton MR spectroscopic study.
JF American Journal of Neuroradiology
JO Am. J. Neuroradiol.
FD American Society of Neuroradiology
SP 648
OP 652
VO 19
IS 4
A1 Falini, A
A1 Barkovich, A J
A1 Calabrese, G
A1 Origgi, D
A1 Triulzi, F
A1 Scotti, G
YR 1998
UL http://www.ajnr.org/content/19/4/648.abstract
AB The findings at sequential MR imaging and proton MR spectroscopy of a patient with profound hypoxic-ischemic brain injury are reported. The pattern of structural and biochemical changes observed closely reflected the known evolution of postasphyxic brain degeneration. Particularly noteworthy were the sharp decrease of cortical N-acetylaspartate in the acute phase, suggesting the severity of the neuronal insult, and the subsequent progressive increase of choline, paralleling the delayed degeneration of white matter.