RT Journal Article
SR Electronic
T1 Influence of T1-Weighted Signal Intensity on FSL Voxel-Based Morphometry and FreeSurfer Cortical Thickness
JF American Journal of Neuroradiology
JO Am. J. Neuroradiol.
FD American Society of Neuroradiology
SP 726
OP 728
DO 10.3174/ajnr.A5053
VO 38
IS 4
A1 Chung, S.
A1 Wang, X.
A1 Lui, Y.W.
YR 2017
UL http://www.ajnr.org/content/38/4/726.abstract
AB SUMMARY: The effect of T1 signal on FSL voxel-based morphometry modulated GM density and FreeSurfer cortical thickness is explored. The techniques rely on different analyses, but both are commonly used to detect spatial changes in GM. Standard pipelines show FSL voxel-based morphometry is sensitive to T1 signal alterations within a physiologic range, and results can appear discordant between FSL voxel-based morphometry and FreeSurfer cortical thickness. Care should be taken in extrapolating results to the effect on brain volume.CTcortical thicknessmGMmodulated GM densitymTBImild traumatic brain injuryVBMvoxel-based morphometry