PT  - JOURNAL ARTICLE
AU  - Cronqvist, S E
AU  - Kullberg, G
TI  - Stereotaxic lesion as a model of brain edema.
DP  - 1983 May 01
TA  - American Journal of Neuroradiology
PG  - 722--724
VI  - 4
IP  - 3
4099  - http://www.ajnr.org/content/4/3/722.short
4100  - http://www.ajnr.org/content/4/3/722.full
SO  - Am. J. Neuroradiol.1983 May 01; 4
AB  - Repeated computed tomographic (CT) examinations after thalamotomy showed a lesion vrying in size over time. This variation was interpreted as indicating presence of an edema. The effect of steroid treatment upon such an edema was tested in a pilot study of 28 patients, 16 of whom were given betamethasone. The diameter of the lesion as observed on CT was used as a measure of the amount of edema. The mean diameter was significantly lower in the steroid-treated group as compared with controls (p less than 0.01, Mann-Whitney U test). The groups were comparable with respect to other variables that might influence lesion size. It is concluded that steroid treatment has an edema-preventing effect.