PT - JOURNAL ARTICLE AU - Kish, K K AU - Rapp, S M AU - Wilner, H I AU - Wolfe, D AU - Thomas, L M AU - Barr, J TI - Histopathologic effects of transarterial bucrylate occlusion of intracerebral arteries in mongrel dogs. DP - 1983 May 01 TA - American Journal of Neuroradiology PG - 385--387 VI - 4 IP - 3 4099 - http://www.ajnr.org/content/4/3/385.short 4100 - http://www.ajnr.org/content/4/3/385.full SO - Am. J. Neuroradiol.1983 May 01; 4 AB - Bucrylate was injected directly into the cerebral cortical arteries of mongrel dogs. Preparations for light and electron microscopy were obtained from 5 min to 5 months after the introduction of the polymer. A mixed pattern of damage to arterial endothelium was seen, including electron microscopic documentation of stripping away of the endothelium. Acute effects include a subocclusive thrombogenic matrix, which causes partial or complete thrombosis. The long-term reactions are those of a chronic inflammatory response to a foreign body.