RT Journal Article
SR Electronic
T1 Iohexol in lumbar myelography: preliminary results from an open, noncomparative multicenter clinical study.
JF American Journal of Neuroradiology
JO Am. J. Neuroradiol.
FD American Society of Neuroradiology
SP 299
OP 301
VO 4
IS 3
A1 Eldevik, O P
A1 Nakstad, P
A1 Kendall, B E
A1 Hindmarsh, T
YR 1983
UL http://www.ajnr.org/content/4/3/299.abstract
AB This is a preliminary report of the first clinical trials using iohexol as a contrast agent in lumbar myelography. The study was noncomparative and involved 82 adult patients in four centers. Iohexol doses of 10-15 ml (180 mg I/ml) were administered and clinical and laboratory tests were performed before and at intervals during 48 hr after myelography. Side effects were noted in 29 (35%) of 82 patients. Spinal repuncture 6 or 24 hr after myelography was performed in 51 patients. No significant increases in cerebrospinal fluid parameters were seen. No seizures or spikes on electroencephalography were seen.