RT Journal Article
SR Electronic
T1 Cortical Involvement in Marchiafava-Bignami Disease
JF American Journal of Neuroradiology
JO Am. J. Neuroradiol.
FD American Society of Neuroradiology
SP 670
OP 673
VO 26
IS 3
A1 Johkura, Ken
A1 Naito, Makoto
A1 Naka, Takayuki
YR 2005
UL http://www.ajnr.org/content/26/3/670.abstract
AB Summary: Marchiafava-Bignami disease (MBD), a rare complication of chronic alcoholism, is characterized by primary demyelination of the corpus callosum. We report two cases of MBD in which fluid-attenuated inversion recovery (FLAIR) and diffusion-weighted imaging studies revealed symmetrical hyperintense lesions in the cerebral cortex (particularly in the lateral-frontal regions) in addition to the callosal lesions, which suggests an association of diffuse cortical lesions such as Morel’s laminar sclerosis with MBD.