PT  - JOURNAL ARTICLE
AU  - Johkura, Ken
AU  - Naito, Makoto
AU  - Naka, Takayuki
TI  - Cortical Involvement in Marchiafava-Bignami Disease
DP  - 2005 Mar 01
TA  - American Journal of Neuroradiology
PG  - 670--673
VI  - 26
IP  - 3
4099  - http://www.ajnr.org/content/26/3/670.short
4100  - http://www.ajnr.org/content/26/3/670.full
SO  - Am. J. Neuroradiol.2005 Mar 01; 26
AB  - Summary: Marchiafava-Bignami disease (MBD), a rare complication of chronic alcoholism, is characterized by primary demyelination of the corpus callosum. We report two cases of MBD in which fluid-attenuated inversion recovery (FLAIR) and diffusion-weighted imaging studies revealed symmetrical hyperintense lesions in the cerebral cortex (particularly in the lateral-frontal regions) in addition to the callosal lesions, which suggests an association of diffuse cortical lesions such as Morel’s laminar sclerosis with MBD.