RT Journal Article
SR Electronic
T1 Usefulness of the Apparent Diffusion Coefficient in Line Scan Diffusion-Weighted Imaging for Distinguishing between Squamous Cell Carcinomas and Malignant Lymphomas of the Head and Neck
JF American Journal of Neuroradiology
JO Am. J. Neuroradiol.
FD American Society of Neuroradiology
SP 1186
OP 1192
VO 26
IS 5
A1 Maeda, Masayuki
A1 Kato, Hiroya
A1 Sakuma, Hajime
A1 Maier, Stephan E.
A1 Takeda, Kan
YR 2005
UL http://www.ajnr.org/content/26/5/1186.abstract
AB BACKGROUND AND PURPOSE: Squamous cell carcinoma (SCC) and lymphoma are common malignant tumors of the head and neck. The purpose of this study was to determine whether the apparent diffusion coefficient (ADC) in line scan diffusion-weighted imaging (LSDWI) is useful for distinguishing between SCC and lymphoma of the head and neck.METHODS: LSDWI was prospectively performed in 39 patients with SCC and in 14 patients with lymphoma. Images were obtained with a diffusion-weighted factor (b factor) of 5 and 1000 s/mm2, and ADC maps were generated. ADC values were measured for the two types of tumor.RESULTS: Mean ADC values were 0.96 ± 0.11 × 10−3 mm2/s for SCC and 0.65 ± 0.09 × 10−3 mm2/s for lymphoma; the difference was significant (P < .001). All but one of the patients with lymphoma had ADC values lower than the lowest ADC (0.76 × 10−3 mm2/s) in patients with SCC. When an ADC of 0.76 × 10−3 mm2/s was used to distinguish between SCC and lymphoma, accuracy was 98% (52 of 53 lesions).CONCLUSION: ADC values appear to be useful for distinguishing between SCC and lymphoma in the head and neck.