PT  - JOURNAL ARTICLE
AU  - Gemmete, J.J.
AU  - Mukherji, S.K.
TI  - Trastuzumab (Herceptin)
AID  - 10.3174/ajnr.A2619
DP  - 2011 Sep 01
TA  - American Journal of Neuroradiology
PG  - 1373--1374
VI  - 32
IP  - 8
4099  - http://www.ajnr.org/content/32/8/1373.short
4100  - http://www.ajnr.org/content/32/8/1373.full
SO  - Am. J. Neuroradiol.2011 Sep 01; 32
AB  - SUMMARY: Herceptin (trastuzumab) is a human monoclonal antibody that interferes with the HER2 receptor. It is currently the only FDA-approved therapeutic antibody for HER2-positive breast cancer. This article will present the mechanism at action as well as the clinical role at this monoclonal antibody. FDAUS Food and Drug AdministrationHER, HER2, HER3, and HER4human epidermal growth factor receptors