PT - JOURNAL ARTICLE AU - Essig, M. AU - Anzalone, N. AU - Combs, S.E. AU - Dörfler, A. AU - Lee, S.-K. AU - Picozzi, P. AU - Rovira, À. AU - Weller, M. AU - Law, M. TI - MR Imaging of Neoplastic Central Nervous System Lesions: Review and Recommendations for Current Practice AID - 10.3174/ajnr.A2640 DP - 2012 May 01 TA - American Journal of Neuroradiology PG - 803--817 VI - 33 IP - 5 4099 - http://www.ajnr.org/content/33/5/803.short 4100 - http://www.ajnr.org/content/33/5/803.full SO - Am. J. Neuroradiol.2012 May 01; 33 AB - SUMMARY: MR imaging is the preferred technique for the diagnosis, treatment planning, and monitoring of patients with neoplastic CNS lesions. Conventional MR imaging, with gadolinium-based contrast enhancement, is increasingly combined with advanced, functional MR imaging techniques to offer morphologic, metabolic, and physiologic information. This article provides updated recommendations to neuroradiologists, neuro-oncologists, neurosurgeons, and radiation oncologists on the practical applications of MR imaging of neoplastic CNS lesions in adults, with particular focus on gliomas, based on a review of the clinical trial evidence and personal experiences shared at a recent international meeting of experts in neuroradiology, neuro-oncology, neurosurgery, and radio-oncology. ADCapparent diffusion coefficientCBVcerebral blood volumeCNScentral nervous systemDCEdynamic contrast-enhancedDSCdynamic susceptibility contrastDTIdiffusion tensor imagingDWIdiffusion-weighted imagingFLAIRfluid-attenuated inversion recoveryFSEfast spin-echoGFRglomerular filtration rateGREgradient recalled-echoKtransvolume transfer coefficientMRSMR spectroscopyPETpositron-emission tomographyPWIperfusion-weighted imagingrCBVrelative cerebral blood volumeTSEturbo spin-echo