PT - JOURNAL ARTICLE AU - Chow, M. AU - McDougall, C. AU - O'Kelly, C. AU - Ashforth, R. AU - Johnson, E. AU - Fiorella, D. TI - Delayed Spontaneous Rupture of a Posterior Inferior Cerebellar Artery Aneurysm Following Treatment with Flow Diversion: A Clinicopathologic Study AID - 10.3174/ajnr.A2532 DP - 2012 Apr 01 TA - American Journal of Neuroradiology PG - E46--E51 VI - 33 IP - 4 4099 - http://www.ajnr.org/content/33/4/E46.short 4100 - http://www.ajnr.org/content/33/4/E46.full SO - Am. J. Neuroradiol.2012 Apr 01; 33 AB - SUMMARY: In this report, we present the fatal spontaneous delayed rupture of a previously unruptured large PICA aneurysm following treatment with the PED. Pathology at postmortem examination has supported the theory that intra-aneurysmal thrombus may acutely destabilize the aneurysm wall. Aneurysms with an anatomic arrangement that promote continued flow into the neck may not be optimal candidates for the flow-diversion treatment strategy. AAAabdominal aortic aneurysmASanterior spinal arteryBbasilarHEhematoxylin-eosinILTintraluminal thrombusLAICleft anterior inferior cerebellar arteryLVleft vertebral arteryMmedullaMRAMR angiographyPponsPEDPipeline Embolization DevicePICAposterior inferior cerebellar arterypO2partial pressure of oxygenPODpostoperative dayRPICright posterior inferior cerebellar arteryRVright vertebral artery