RT Journal Article
SR Electronic
T1 Pericarotid Fat as a Marker of Cerebrovascular Risk
JF American Journal of Neuroradiology
JO Am. J. Neuroradiol.
FD American Society of Neuroradiology
SP 1635
OP 1641
DO 10.3174/ajnr.A8300
VO 45
IS 11
A1 Cau, Riccardo
A1 Anzalone, Nicoletta
A1 Mannelli, Lorenzo
A1 Edjlali, Myriam
A1 Balestrieri, Antonella
A1 Nardi, Valentina
A1 Lanzino, Giuseppe
A1 Lerman, Amir
A1 Suri, Jasjit S.
A1 Saba, Luca
YR 2024
UL http://www.ajnr.org/content/45/11/1635.abstract
AB Vascular inflammation is widely recognized as an important factor in the atherosclerotic process, particularly in terms of plaque development and progression. Conventional tests, such as measuring circulating inflammatory biomarkers, lack the precision to identify specific areas of vascular inflammation. In this context, noninvasive imaging modalities can detect perivascular fat changes, serving as a marker of vascular inflammation. This review aims to provide a comprehensive overview of the key concepts related to perivascular carotid fat and its pathophysiology. Additionally, we examine the existing literature on the association of pericarotid fat with features of plaque vulnerability and cerebrovascular events. Finally, we scrutinize the advantages and limitations of the noninvasive assessment of pericarotid fat.AIartificial intelligenceAUCarea under the curveHUHounsfield unitPCFpericarotid fatPVATperivascular adipose tissueUSultrasoundUSPIOultra-small superparamagnetic iron oxide particles