PT  - JOURNAL ARTICLE
AU  - Schievink, Wouter I.
AU  - Maya, Marcel M.
AU  - Nuño, Miriam
TI  - De Novo Formation of Idiopathic Spinal Cord Herniation
AID  - 10.3174/ajnr.A8338
DP  - 2024 Jul 25
TA  - American Journal of Neuroradiology
4099  - http://www.ajnr.org/content/early/2024/07/25/ajnr.A8338.short
4100  - http://www.ajnr.org/content/early/2024/07/25/ajnr.A8338.full
AB  - We investigated whether idiopathic spinal cord herniation is a congenital or acquired condition and undertook a study to determine the risk of developing iSCH in patients with persistent ventral spinal CSF leaks. De novo formation of iSCH was established among all 6 patients with iSCH who had undergone prior spinal imaging for symptoms unrelated to iSCH. Among 51 patients with persistent ventral spinal CSF leaks, iSCH developed in 2 patients (probability increased from 0% at 5 years to 9.4% at 10 years). This study shows that iSCH is an acquired condition, and early treatment of ventral CSF leaks offers a unique opportunity to prevent neurologic disability.iSCHidiopathic spinal cord herniationSIHspontaneous intracranial hypotensionSCHspinal cord herniationSDstandard deviation