RT Journal Article SR Electronic T1 Epstein-Barr Virus–Associated Smooth-Muscle Tumor of the Brain JF American Journal of Neuroradiology JO Am. J. Neuroradiol. FD American Society of Neuroradiology SP 850 OP 854 DO 10.3174/ajnr.A8258 VO 45 IS 7 A1 Alfalahi, Afra A1 Omar, Abdelsimar Il A1 Fox, Krystal A1 Spears, Julian A1 Sharma, Malika A1 Bharatha, Aditya A1 Munoz, David G. A1 Suthiphosuwan, Suradech YR 2024 UL http://www.ajnr.org/content/45/7/850.abstract AB Epstein-Barr virus, a herpesvirus, has been associated with a variety of cancers, including Burkitt, Hodgkin, and non-Hodgkin lymphomas; posttransplant lymphoproliferative disorders; gastric carcinoma; and nasopharyngeal carcinoma, in both immunocompetent and immunocompromised individuals. Previous studies have established a connection between Epstein-Barr virus and the development of smooth-muscle tumors. Smooth-muscle tumors of the brain are very rare and are often misdiagnosed as meningiomas on imaging. To our knowledge, advanced imaging findings such as MR perfusion of smooth-muscle tumors of the brain have never been reported. We describe the radiologic and pathologic features of the Epstein-Barr virus–associated smooth-muscle tumors of the brain in a person with newly diagnosed advanced HIV.EBVEpstein-Barr virusEBV-SMTEpstein-Barr virus–associated smooth-muscle tumorrCBVrelative CBVSMTsmooth-muscle tumor