RT Journal Article
SR Electronic
T1 Neuropathologic and MR Imaging Correlation in a Neonatal Case of Cerebellar Cortical Dysplasia
JF American Journal of Neuroradiology
JO Am. J. Neuroradiol.
FD American Society of Neuroradiology
SP 1101
OP 1104
VO 23
IS 7
A1 Soto-Ares, Gustavo
A1 Devisme, Louise
A1 Jorriot, Sylvie
A1 Deries, Berengere
A1 Pruvo, Jean P.
A1 Ruchoux, Marie M.
YR 2002
UL http://www.ajnr.org/content/23/7/1101.abstract
AB Little documentation of the correlation between MR imaging findings in isolated cerebellar cortical dysplasia (CCD) and its neuropathologic characteristics exists in the recent literature. We documented a postmortem neuropathologic study of a clinically and radiologically well-documented case of CCD in a neonate with severe hypotonia and status epilepticus. MR imaging revealed a global vermian hypoplasia with marked cortical dysplasia. CCD was associated with a voluminous heterotopic mass. The postmortem neuropathologic study confirmed vermian hypoplasia and CCD, which consisted of right cerebellar cortical polymicrogyria with subcortical heterotopia. CCD is a pathologic entity that could be well diagnosed with MR imaging even in the neonatal period.