RT Journal Article
SR Electronic
T1 Symptomatic Developmental Venous Anomaly: State-of-the-Art Review on Genetics, Pathophysiology, and Imaging Approach to Diagnosis
JF American Journal of Neuroradiology
JO Am. J. Neuroradiol.
FD American Society of Neuroradiology
DO 10.3174/ajnr.A7829
A1 Hsu, C.C.-T.
A1 Krings, T.
YR 2023
UL http://www.ajnr.org/content/early/2023/03/30/ajnr.A7829.abstract
AB SUMMARY: Developmental venous anomalies (DVAs) are the most common slow-flow venous malformation in the brain. Most DVAs are benign. Uncommonly, DVAs can become symptomatic, leading to a variety of different pathologies. DVAs can vary significantly in size, location, and angioarchitecture, and imaging evaluation of symptomatic developmental venous anomalies requires a systematic approach. In this review, we aimed to provide neuroradiologists with a succinct overview of the genetics and categorization of symptomatic DVAs based on the pathogenesis, which forms the foundation for a tailored neuroimaging approach to assist in diagnosis and management.BRBNSblue rubber bleb nevus syndromeCCMcerebral cavernous malformationCMMRDconstitutional mismatch repair deficiency syndromeCVMScerebrofacial venous metameric syndromeDVAdevelopmental venous anomalyWMHwhite matter hyperintensities