PT  - JOURNAL ARTICLE
AU  - Rigsby, R.K.
AU  - Brahmbhatt, P.
AU  - Desai, A.B.
AU  - Bathla, G.
AU  - Ebner, B.A.
AU  - Gupta, V.
AU  - Vibhute, P.
AU  - Agarwal, A.K.
TI  - Newly Recognized CNS Tumors in the 2021 World Health Organization Classification: Imaging Overview with Histopathologic and Genetic Correlation
AID  - 10.3174/ajnr.A7827
DP  - 2023 Mar 30
TA  - American Journal of Neuroradiology
4099  - http://www.ajnr.org/content/early/2023/03/30/ajnr.A7827.short
4100  - http://www.ajnr.org/content/early/2023/03/30/ajnr.A7827.full
AB  - SUMMARY: In 2021, the World Health Organization released an updated classification of CNS tumors. This update reflects the growing understanding of the importance of genetic alterations related to tumor pathogenesis, prognosis, and potential targeted treatments and introduces 22 newly recognized tumor types. Herein, we review these 22 newly recognized entities and emphasize their imaging appearance with correlation to histologic and genetic features.AT/RTatypical teratoid/rhabdoid tumorcIMPACT-NOWConsortium to Inform Molecular and Practical Approaches to CNS Tumor Taxonomy-Not Official WHOGFAPglial fibrillary acidic proteinMAPKmitogen-activated protein kinaseNECnot elsewhere classifiedNOSnot otherwise specifiedPFA and PFBposterior fossa ependymoma groups A and BWHOWorld Health OrganizationWHO CNS5World Health Organization Classification of Tumors of the Central Nervous System, fifth editionIDHisocitrate dehydrogenase