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AJNR Awards, New Junior Editors, and more. Read the latest AJNR updates

Research ArticlePediatric Neuroimaging
Open Access

Nonmicrocephalic Infants with Congenital Zika Syndrome Suspected Only after Neuroimaging Evaluation Compared with Those with Microcephaly at Birth and Postnatally: How Large Is the Zika Virus “Iceberg”?

M.F.V.V. Aragao, A.C. Holanda, A.M. Brainer-Lima, N.C.L. Petribu, M. Castillo, V. van der Linden, S.C. Serpa, A.G. Tenório, P.T.C. Travassos, M.T. Cordeiro, C. Sarteschi, M.M. Valenca and A. Costello
American Journal of Neuroradiology July 2017, 38 (7) 1427-1434; DOI: https://doi.org/10.3174/ajnr.A5216
M.F.V.V. Aragao
aFrom the Centro Diagnostico Multimagem (M.F.V.V.A.), Recife, Brazil
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A.C. Holanda
bFederal University of Pernambuco (A.C.H.), Recife, Brazil
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A.M. Brainer-Lima
cPronto-Socorro Cardiológico de Pernambuco (Procape) (A.M.B.-L., M.M.V.), University of Pernambuco, Recife, Brazil
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N.C.L. Petribu
dBarão de Lucena Hospital (N.C.L.P.), Recife, Brazil
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M. Castillo
eDepartment of Radiology (M.C.), University of North Carolina, Chapel Hill, North Carolina
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V. van der Linden
fAssociation for Assistance of Disabled Children (V.v.d.L.), Recife, Brazil
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S.C. Serpa
gClínica de Apoio Ocupacional (S.C.S.), Jaboatão dos Guararapes, Brazil
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A.G. Tenório
hDom Malan Hospital (A.G.T.), Petrolina, Brazil
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P.T.C. Travassos
iLaboratório Fernando Travassos (P.T.C.T.), Recife, Brazil
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M.T. Cordeiro
jCentro de Pesquisas Aggeu Magalhães (M.T.C., C.S.), Fiocruz, Recife, Brazil
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C. Sarteschi
jCentro de Pesquisas Aggeu Magalhães (M.T.C., C.S.), Fiocruz, Recife, Brazil
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M.M. Valenca
cPronto-Socorro Cardiológico de Pernambuco (Procape) (A.M.B.-L., M.M.V.), University of Pernambuco, Recife, Brazil
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A. Costello
kDepartment of Maternal, Child, and Adolescent Health (A.C.), World Health Organization, Geneva, Switzerland.
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American Journal of Neuroradiology: 38 (7)
American Journal of Neuroradiology
Vol. 38, Issue 7
1 Jul 2017
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M.F.V.V. Aragao, A.C. Holanda, A.M. Brainer-Lima, N.C.L. Petribu, M. Castillo, V. van der Linden, S.C. Serpa, A.G. Tenório, P.T.C. Travassos, M.T. Cordeiro, C. Sarteschi, M.M. Valenca, A. Costello
Nonmicrocephalic Infants with Congenital Zika Syndrome Suspected Only after Neuroimaging Evaluation Compared with Those with Microcephaly at Birth and Postnatally: How Large Is the Zika Virus “Iceberg”?
American Journal of Neuroradiology Jul 2017, 38 (7) 1427-1434; DOI: 10.3174/ajnr.A5216

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Nonmicrocephalic Infants with Congenital Zika Syndrome Suspected Only after Neuroimaging Evaluation Compared with Those with Microcephaly at Birth and Postnatally: How Large Is the Zika Virus “Iceberg”?
M.F.V.V. Aragao, A.C. Holanda, A.M. Brainer-Lima, N.C.L. Petribu, M. Castillo, V. van der Linden, S.C. Serpa, A.G. Tenório, P.T.C. Travassos, M.T. Cordeiro, C. Sarteschi, M.M. Valenca, A. Costello
American Journal of Neuroradiology Jul 2017, 38 (7) 1427-1434; DOI: 10.3174/ajnr.A5216
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Cited By...

  • Saxitoxin potentiates Zika virus-induced cell death in human neurons but not in neural progenitors and astrocytes
  • A Zika virus protein expression screen in Drosophila to investigate targeted host pathways during development
  • Neurodevelopment in normocephalic children with and without prenatal Zika virus exposure
  • Zika Virus Congenital Microcephaly Severity Classification and the Association of Severity with Neuropsychomotor Development
  • Neuroanatomical abnormalities in a nonhuman primate model of congenital Zika virus infection
  • Zika Virus Infection: Review Of Neuroimage Studies And The Relationship Between Findings And Time Of Infection
  • Life-long persistence of infectious Zika virus: inflammation and behavioral sequela
  • Long-term alterations in brain and behavior after postnatal Zika virus infections in infant macaques
  • Mouse Strain and Sex-Dependent Differences in Long-term Behavioral Abnormalities and Neuropathologies after Developmental Zika Infection
  • CImP: Cellular Imprinting Proteomics applied to ocular disorders elicited by Congenital Zika virus Syndrome
  • Zika Virus Infection at Different Pregnancy Stages: Anatomopathological Findings, Target Cells and Viral Persistence in Placental Tissues
  • Postnatal Zika virus infection is associated with persistent abnormalities in brain structure, function, and behavior in infant macaques
  • Zika Virus Iceberg: Very Large
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