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Research ArticleBrain

Interscanner Variation in Brain MR Lesion Load Measurements in Multiple Sclerosis Using Conventional Spin-Echo, Rapid Relaxation-Enhanced, and Fast-FLAIR Sequences

Massimo Filippi, Maria A. Rocca, Claudio Gasperini, Maria P. Sormani, Stefano Bastianello, Mark A. Horsfield, Carlo Pozzilli and Giancarlo Comi
American Journal of Neuroradiology January 1999, 20 (1) 133-137;
Massimo Filippi
aFrom the Neuroimaging Research Unit (M.F., M.A.R., M.P.S.) and Clinical Trials Unit (G.C.), Department of Neuroscience, Scientific Institute Ospedale San Raffaele, University of Milan; Departments of Neurology (C.G., C.P.) and Neuroradiology (S.B.), Università “La Sapienza,” Rome; Department of Neurology (C.G.), San Camillo Hospital, Rome; Unit of Clinical Epidemiology and Trials (M.P.S.), Institute for Cancer Research, Genoa, Italy; and Division of Medical Physics (M.A.H.), University of Leicester, Leicester, UK.
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Maria A. Rocca
aFrom the Neuroimaging Research Unit (M.F., M.A.R., M.P.S.) and Clinical Trials Unit (G.C.), Department of Neuroscience, Scientific Institute Ospedale San Raffaele, University of Milan; Departments of Neurology (C.G., C.P.) and Neuroradiology (S.B.), Università “La Sapienza,” Rome; Department of Neurology (C.G.), San Camillo Hospital, Rome; Unit of Clinical Epidemiology and Trials (M.P.S.), Institute for Cancer Research, Genoa, Italy; and Division of Medical Physics (M.A.H.), University of Leicester, Leicester, UK.
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Claudio Gasperini
aFrom the Neuroimaging Research Unit (M.F., M.A.R., M.P.S.) and Clinical Trials Unit (G.C.), Department of Neuroscience, Scientific Institute Ospedale San Raffaele, University of Milan; Departments of Neurology (C.G., C.P.) and Neuroradiology (S.B.), Università “La Sapienza,” Rome; Department of Neurology (C.G.), San Camillo Hospital, Rome; Unit of Clinical Epidemiology and Trials (M.P.S.), Institute for Cancer Research, Genoa, Italy; and Division of Medical Physics (M.A.H.), University of Leicester, Leicester, UK.
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Maria P. Sormani
aFrom the Neuroimaging Research Unit (M.F., M.A.R., M.P.S.) and Clinical Trials Unit (G.C.), Department of Neuroscience, Scientific Institute Ospedale San Raffaele, University of Milan; Departments of Neurology (C.G., C.P.) and Neuroradiology (S.B.), Università “La Sapienza,” Rome; Department of Neurology (C.G.), San Camillo Hospital, Rome; Unit of Clinical Epidemiology and Trials (M.P.S.), Institute for Cancer Research, Genoa, Italy; and Division of Medical Physics (M.A.H.), University of Leicester, Leicester, UK.
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Stefano Bastianello
aFrom the Neuroimaging Research Unit (M.F., M.A.R., M.P.S.) and Clinical Trials Unit (G.C.), Department of Neuroscience, Scientific Institute Ospedale San Raffaele, University of Milan; Departments of Neurology (C.G., C.P.) and Neuroradiology (S.B.), Università “La Sapienza,” Rome; Department of Neurology (C.G.), San Camillo Hospital, Rome; Unit of Clinical Epidemiology and Trials (M.P.S.), Institute for Cancer Research, Genoa, Italy; and Division of Medical Physics (M.A.H.), University of Leicester, Leicester, UK.
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Mark A. Horsfield
aFrom the Neuroimaging Research Unit (M.F., M.A.R., M.P.S.) and Clinical Trials Unit (G.C.), Department of Neuroscience, Scientific Institute Ospedale San Raffaele, University of Milan; Departments of Neurology (C.G., C.P.) and Neuroradiology (S.B.), Università “La Sapienza,” Rome; Department of Neurology (C.G.), San Camillo Hospital, Rome; Unit of Clinical Epidemiology and Trials (M.P.S.), Institute for Cancer Research, Genoa, Italy; and Division of Medical Physics (M.A.H.), University of Leicester, Leicester, UK.
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Carlo Pozzilli
aFrom the Neuroimaging Research Unit (M.F., M.A.R., M.P.S.) and Clinical Trials Unit (G.C.), Department of Neuroscience, Scientific Institute Ospedale San Raffaele, University of Milan; Departments of Neurology (C.G., C.P.) and Neuroradiology (S.B.), Università “La Sapienza,” Rome; Department of Neurology (C.G.), San Camillo Hospital, Rome; Unit of Clinical Epidemiology and Trials (M.P.S.), Institute for Cancer Research, Genoa, Italy; and Division of Medical Physics (M.A.H.), University of Leicester, Leicester, UK.
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Giancarlo Comi
aFrom the Neuroimaging Research Unit (M.F., M.A.R., M.P.S.) and Clinical Trials Unit (G.C.), Department of Neuroscience, Scientific Institute Ospedale San Raffaele, University of Milan; Departments of Neurology (C.G., C.P.) and Neuroradiology (S.B.), Università “La Sapienza,” Rome; Department of Neurology (C.G.), San Camillo Hospital, Rome; Unit of Clinical Epidemiology and Trials (M.P.S.), Institute for Cancer Research, Genoa, Italy; and Division of Medical Physics (M.A.H.), University of Leicester, Leicester, UK.
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Cite this article
Massimo Filippi, Maria A. Rocca, Claudio Gasperini, Maria P. Sormani, Stefano Bastianello, Mark A. Horsfield, Carlo Pozzilli, Giancarlo Comi
Interscanner Variation in Brain MR Lesion Load Measurements in Multiple Sclerosis Using Conventional Spin-Echo, Rapid Relaxation-Enhanced, and Fast-FLAIR Sequences
American Journal of Neuroradiology Jan 1999, 20 (1) 133-137;

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Interscanner Variation in Brain MR Lesion Load Measurements in Multiple Sclerosis Using Conventional Spin-Echo, Rapid Relaxation-Enhanced, and Fast-FLAIR Sequences
Massimo Filippi, Maria A. Rocca, Claudio Gasperini, Maria P. Sormani, Stefano Bastianello, Mark A. Horsfield, Carlo Pozzilli, Giancarlo Comi
American Journal of Neuroradiology Jan 1999, 20 (1) 133-137;
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  • A Comparison of MR Imaging with Fast-FLAIR, HASTE-FLAIR, and EPI-FLAIR Sequences in the Assessment of Patients with Multiple Sclerosis
  • Relevance of Hypointense Lesions on Fast Fluid-Attenuated Inversion Recovery MR Images as a Marker of Disease Severity in Cases of Multiple
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