Mechanism of tumor rejection with doublets of CTLA-4, PD-1/PD-L1, or IDO blockade involves restored IL-2 production and proliferation of CD8+ T cells directly within the tumor microenvironment ================================================================================================================================================================================================ * Stefani Spranger * Holly K Koblish * Brendan Horton * Peggy A Scherle * Robert Newton * Thomas F Gajewski