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Dynamical modeling of proliferative-invasive plasticity and IFNγ signaling in melanoma reveals mechanisms of PD-L1 expression heterogeneity
Seemadri Subhadarshini, Sarthak Sahoo, Shibjyoti Debnath, Jason A Somarelli, Mohit Kumar Jolly

Journal for ImmunoTherapy of Cancer Sep 2023, 11 (9) e006766; DOI: 10.1136/jitc-2023-006766
Bispecific antibody CD73xEGFR more selectively inhibits the CD73/adenosine immune checkpoint on cancer cells and concurrently counteracts pro-oncogenic activities of CD73 and EGFR
Emily Maria Ploeg, Douwe Freerk Samplonius, Xiao Xiong, Xiurong Ke, Mark Alexander Johannes Martinus Hendriks, Isabel Britsch, Anne Paulien van Wijngaarden, Hao Zhang, Wijnand Helfrich

Journal for ImmunoTherapy of Cancer Sep 2023, 11 (9) e006837; DOI: 10.1136/jitc-2023-006837
Inhibition of TCA cycle improves the anti-PD-1 immunotherapy efficacy in melanoma cells via ATF3-mediated PD-L1 expression and glycolysis
Nian Liu, Mingjie Yan, Qian Tao, Jie Wu, Jing Chen, Xiang Chen, Cong Peng

Journal for ImmunoTherapy of Cancer Sep 2023, 11 (9) e007146; DOI: 10.1136/jitc-2023-007146
Polymorphonuclear myeloid-derived suppressor cells and phosphatidylinositol-3 kinase gamma are critical to tobacco-mimicking oral carcinogenesis in mice
Khoa A Nguyen, Lisa N DePledge, Li Bian, Yao Ke, Von Samedi, Amber A Berning, Philip Owens, Xiao-Jing Wang, Christian D Young

Journal for ImmunoTherapy of Cancer Sep 2023, 11 (9) e007110; DOI: 10.1136/jitc-2023-007110
Cell-free DNA approaches for cancer early detection and interception
Jamie E Medina, Nicholas C Dracopoli, Peter B Bach, Anna Lau, Robert B Scharpf, Gerrit A Meijer, Claus Lindbjerg Andersen, Victor E Velculescu

Journal for ImmunoTherapy of Cancer Sep 2023, 11 (9) e006013; DOI: 10.1136/jitc-2022-006013
Machine learning-based integration develops a metabolism-derived consensus model for improving immunotherapy in pancreatic cancer
Yongdong Guo, Ronglin Wang, Jingjie Shi, Cheng Yang, Peixiang Ma, Jie Min, Ting Zhao, Lei Hua, Yang Song, Junqiang Li, Haichuan Su

Journal for ImmunoTherapy of Cancer Sep 2023, 11 (9) e007466; DOI: 10.1136/jitc-2023-007466
Brave new world of cfDNA-omics for early cancer detection
Christian Rolfo, Alessandro Russo

Journal for ImmunoTherapy of Cancer Sep 2023, 11 (9) e006309; DOI: 10.1136/jitc-2022-006309
RIG-I promotes immune evasion of colon cancer by modulating PD-L1 ubiquitination
Yangyang Zhang, Lingxiu Zeng, Meng Wang, Zhenwei Yang, Hailin Zhang, Liping Gao, Ranran Zhang, Jialong Liu, Wenqing Shan, Ying Chang, Lan Liu, Qiu Zhao, Yong Li, Jing Liu

Journal for ImmunoTherapy of Cancer Sep 2023, 11 (9) e007313; DOI: 10.1136/jitc-2023-007313
Hsa-LINC02418/mmu-4930573I07Rik regulated by METTL3 dictates anti-PD-L1 immunotherapeutic efficacy via enhancement of Trim21-mediated PD-L1 ubiquitination
Zhijia Sun, Haixing Mai, Chunyuan Xue, Zhongyi Fan, Jiangbo Li, Hairui Chen, Nan Huo, Xiaofeng Kang, Chuanhao Tang, Liaoxin Fang, Hui Zhao, Yuchen Han, Chao Sun, Huanyan Peng, Yimeng Du, Jing Yang, Nan Du, Xiaojie Xu

Journal for ImmunoTherapy of Cancer Dec 2023, 11 (12) e007415; DOI: 10.1136/jitc-2023-007415
Targeting integrin α5 in fibroblasts potentiates colorectal cancer response to PD-L1 blockade by affecting extracellular-matrix deposition
Ling Lu, Yaohui Gao, Dengfeng Huang, Hu Liu, Dingzi Yin, Man Li, Jiayi Zheng, Shufei Wang, Weijun Wu, Li Zhao, Dexi Bi, Youhua Zhang, Feifei Song, Ruting Xie, Jifeng Wang, Huanlong Qin, Qing Wei

Journal for ImmunoTherapy of Cancer Dec 2023, 11 (12) e007447; DOI: 10.1136/jitc-2023-007447

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