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Harnessing novel strategies and cell types to overcome immune tolerance during adoptive cell therapy in cancer
Shi Yong Neo, Shengli Xu, Joni Chong, Kong-Peng Lam, Jing Wu

Journal for ImmunoTherapy of Cancer Apr 2023, 11 (4) e006434; DOI: 10.1136/jitc-2022-006434
BRD4 inhibition impairs DNA mismatch repair, induces mismatch repair mutation signatures and creates therapeutic vulnerability to immune checkpoint blockade in MMR-proficient tumors
Yu Fu, Bin Yang, Yaoyuan Cui, Xingyuan Hu, Xi Li, Funian Lu, Tianyu Qin, Li Zhang, Zhe Hu, Ensong Guo, Junpeng Fan, Rourou Xiao, Wenting Li, Xu Qin, Dianxing Hu, Wenju Peng, Jingbo Liu, Beibei Wang, Gordon B Mills, Gang Chen, Chaoyang Sun

Journal for ImmunoTherapy of Cancer Apr 2023, 11 (4) e006070; DOI: 10.1136/jitc-2022-006070
Correction: JAK inhibitors and COVID-19
Journal for ImmunoTherapy of Cancer Apr 2023, 11 (4) e002838corr1; DOI: 10.1136/jitc-2021-002838corr1
Barriers to immune cell infiltration in tumors
Marit M Melssen, Natasha D Sheybani, Katie M Leick, Craig L Slingluff

Journal for ImmunoTherapy of Cancer Apr 2023, 11 (4) e006401; DOI: 10.1136/jitc-2022-006401
Vector Aided Microenvironment programming (VAMP): reprogramming the TME with MVA virus expressing IL-12 for effective antitumor activity
Laura Seclì, Luigia Infante, Linda Nocchi, Maria De Lucia, Gabriella Cotugno, Guido Leoni, Elisa Micarelli, Irene Garzia, Lidia Avalle, Giulia Sdruscia, Fulvia Troise, Simona Allocca, Giuseppina Romano, Elisa Scarselli, Anna Morena D'Alise

Journal for ImmunoTherapy of Cancer Apr 2023, 11 (4) e006718; DOI: 10.1136/jitc-2023-006718
Ectopic expression of cGAS in Salmonella typhimurium enhances STING-mediated IFN-β response in human macrophages and dendritic cells
Lisette Waanders, Lieve E H van der Donk, Louis S Ates, Janneke Maaskant, John L van Hamme, Eric Eldering, Jaco A C van Bruggen, Joanne M Rietveld, Wilbert Bitter, Teunis B H Geijtenbeek, Coenraad P Kuijl

Journal for ImmunoTherapy of Cancer Apr 2023, 11 (4) e005839; DOI: 10.1136/jitc-2022-005839
Use of cytokine-induced killer cell therapy in patients with colorectal cancer: a systematic review and meta-analysis
Celine Man Ying Li, Yoko Tomita, Bimala Dhakal, Runhao Li, Jun Li, Paul Drew, Timothy Price, Eric Smith, Guy J Maddern, Kevin Aaron Fenix

Journal for ImmunoTherapy of Cancer Apr 2023, 11 (4) e006764; DOI: 10.1136/jitc-2023-006764
Irreversible electroporation augments β-glucan induced trained innate immunity for the treatment of pancreatic ductal adenocarcinoma
Matthew R Woeste, Rejeena Shrestha, Anne E Geller, Shu Li, Diego Montoya-Durango, Chuanlin Ding, Xiaoling Hu, Hong Li, Aaron Puckett, Robert A Mitchell, Traci Hayat, Min Tan, Yan Li, Kelly M McMasters, Robert C G Martin, Jun Yan

Journal for ImmunoTherapy of Cancer Apr 2023, 11 (4) e006221; DOI: 10.1136/jitc-2022-006221
Cancer cell genotype associated tumor immune microenvironment exhibits differential response to therapeutic STING pathway activation in high-grade serous ovarian cancer
Noor Shakfa, Deyang Li, Gwenaelle Conseil, Elizabeth D Lightbody, Juliette Wilson-Sanchez, Ali Hamade, Stephen Chenard, Natasha A. Jawa, Brian J. Laight, Afrakoma Afriyie-Asante, Kathrin Tyryshkin, Martin Koebel, Madhuri Koti

Journal for ImmunoTherapy of Cancer Apr 2023, 11 (4) e006170; DOI: 10.1136/jitc-2022-006170
Intratumor childhood vaccine-specific CD4⁺ T-cell recall coordinates antitumor CD8⁺ T cells and eosinophils
Michael C Brown, Georgia M Beasley, Zachary P McKay, Yuanfan Yang, Annick Desjardins, Dina M Randazzo, Daniel Landi, David M Ashley, Darell D Bigner, Smita K Nair, Matthias Gromeier

Journal for ImmunoTherapy of Cancer Apr 2023, 11 (4) e006463; DOI: 10.1136/jitc-2022-006463

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