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Safety and efficacy of the tumor-selective adenovirus enadenotucirev with or without paclitaxel in platinum-resistant ovarian cancer: a phase 1 clinical trial
Victor Moreno, Maria-Pilar Barretina-Ginesta, Jesús García-Donas, Gordon C Jayson, Patricia Roxburgh, Raúl Márquez Vázquez, Agnieszka Michael, Antonio Antón-Torres, Richard Brown, David Krige, Brian Champion, Iain McNeish

Journal for ImmunoTherapy of Cancer Dec 2021, 9 (12) e003645; DOI: 10.1136/jitc-2021-003645
Engineering CAR-NK cells to secrete IL-15 sustains their anti-AML functionality but is associated with systemic toxicities
Ilias Christodoulou, Won Jin Ho, Andrew Marple, Jonas W Ravich, Ada Tam, Ruyan Rahnama, Adam Fearnow, Cambrynne Rietberg, Sean Yanik, Elena E Solomou, Ravi Varadhan, Michael A Koldobskiy, Challice L Bonifant

Journal for ImmunoTherapy of Cancer Dec 2021, 9 (12) e003894; DOI: 10.1136/jitc-2021-003894
Genomic and transcriptomic characterization of heterogeneous immune subgroups of microsatellite instability-high colorectal cancers
Jung Ho Kim, Mi-Kyoung Seo, Ji Ae Lee, Seung-Yeon Yoo, Hyeon Jeong Oh, Hyundeok Kang, Nam-Yun Cho, Jeong Mo Bae, Gyeong Hoon Kang, Sangwoo Kim

Journal for ImmunoTherapy of Cancer Dec 2021, 9 (12) e003414; DOI: 10.1136/jitc-2021-003414
Switch receptor T3/28 improves long-term persistence and antitumor efficacy of CAR-T cells
Songbo Zhao, Chunhua Wang, Ping Lu, Yalin Lou, Huimin Liu, Ting Wang, Shanshan Yang, Ziyou Bao, Lin Han, Xiaohong Liang, Chunhong Ma, Lifen Gao

Journal for ImmunoTherapy of Cancer Dec 2021, 9 (12) e003176; DOI: 10.1136/jitc-2021-003176
Combinatorial immunotherapy induces tumor-infiltrating CD8⁺ T cells with distinct functional, migratory, and stem-like properties
Natalija Van Braeckel-Budimir, Joseph Samuel Dolina, Jie Wei, Xiao Wang, Shih-Hsun Chen, Pamela Santiago, Guanghuan Tu, Luca Micci, Amir A Al-Khami, Sophia Pfister, Sripad Ram, Purnima Sundar, Graham Thomas, Hua Long, Wenjing Yang, Shobha Potluri, Shahram Salek-Ardakani

Journal for ImmunoTherapy of Cancer Dec 2021, 9 (12) e003614; DOI: 10.1136/jitc-2021-003614
Correction: Society for Immunotherapy of Cancer (SITC) clinical practice guideline on immunotherapy for the treatment of breast cancer
Journal for ImmunoTherapy of Cancer Dec 2021, 9 (12) e002597corr1; DOI: 10.1136/jitc-2021-002597corr1
Immunogenic ferroptosis and where to find it?
Robin Demuynck, Iuliia Efimova, Faye Naessens, Dmitri V Krysko

Journal for ImmunoTherapy of Cancer Dec 2021, 9 (12) e003430; DOI: 10.1136/jitc-2021-003430
Immunization with short peptide particles reveals a functional CD8⁺ T-cell neoepitope in a murine renal carcinoma model
Xuedan He, Shiqi Zhou, Melissa Dolan, Yuhao Shi, Jianxin Wang, Breandan Quinn, Dushyant Jahagirdar, Wei-Chiao Huang, Moriya Tsuji, Roberto Pili, Fumito Ito, Joaquin Ortega, Scott I Abrams, John M L Ebos, Jonathan F Lovell

Journal for ImmunoTherapy of Cancer Dec 2021, 9 (12) e003101; DOI: 10.1136/jitc-2021-003101
Gut microbiome is associated with the clinical response to anti-PD-1 based immunotherapy in hepatobiliary cancers
Jinzhu Mao, Dongxu Wang, Junyu Long, Xu Yang, Jianzhen Lin, Yiwei Song, Fucun Xie, Ziyu Xun, Yanyu Wang, Yunchao Wang, Yiran Li, Huishan Sun, Jingnan Xue, Yang Song, Bangyou Zuo, Junwei Zhang, Jin Bian, Ting Zhang, Xiaobo Yang, Lei Zhang, Xinting Sang, Haitao Zhao

Journal for ImmunoTherapy of Cancer Dec 2021, 9 (12) e003334; DOI: 10.1136/jitc-2021-003334
Distinct exhaustion features of T lymphocytes shape the tumor-immune microenvironment with therapeutic implication in patients with non-small-cell lung cancer
Chang Gon Kim, Gamin Kim, Kyung Hwan Kim, Seyeon Park, Sunhye Shin, Dahee Yeo, Hyo Sup Shim, Hong In Yoon, Seong Yong Park, Sang-Jun Ha, Hye Ryun Kim

Journal for ImmunoTherapy of Cancer Dec 2021, 9 (12) e002780; DOI: 10.1136/jitc-2021-002780

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