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Therapeutic targeting of PD-1/PD-L1 blockade by novel small-molecule inhibitors recruits cytotoxic T cells into solid tumor microenvironment
Rita C. Acúrcio, Sabina Pozzi, Barbara Carreira, Marta Pojo, Nuria Gómez-Cebrián, Sandra Casimiro, Adelaide Fernandes, Andreia Barateiro, Vitor Farricha, Joaquim Brito, Ana Paula Leandro, Jorge A R Salvador, Luís Graça, Leonor Puchades-Carrasco, Luís Costa, Ronit Satchi-Fainaro, Rita C. Guedes, Helena F. Florindo

Journal for ImmunoTherapy of Cancer Jul 2022, 10 (7) e004695; DOI: 10.1136/jitc-2022-004695
Spatial profiling reveals association between WNT pathway activation and T-cell exclusion in acquired resistance of synovial sarcoma to NY-ESO-1 transgenic T-cell therapy
Katie M Campbell, Maneesha Thaker, Egmidio Medina, Anusha Kalbasi, Arun Singh, Antoni Ribas, Theodore Scott Nowicki

Journal for ImmunoTherapy of Cancer Mar 2022, 10 (3) e004190; DOI: 10.1136/jitc-2021-004190
Lower baseline autoantibody levels are associated with immune-related adverse events from immune checkpoint inhibition
Nilasha Ghosh, Michael Postow, Chengsong Zhu, Deanna Jannat-Khah, Quan-Zhen Li, Greg Vitone, Karmela K Chan, Anne R Bass

Journal for ImmunoTherapy of Cancer Jan 2022, 10 (1) e004008; DOI: 10.1136/jitc-2021-004008
Intratumoral IL-1R1 expression delineates a distinctive molecular subset with therapeutic resistance in patients with gastric cancer
Puran Zhang, Yun Gu, Hanji Fang, Yifan Cao, Jieti Wang, Hao Liu, Heng Zhang, He Li, Hongyong He, Ruochen Li, Chao Lin, Jiejie Xu

Journal for ImmunoTherapy of Cancer Feb 2022, 10 (2) e004047; DOI: 10.1136/jitc-2021-004047
Local and systemic immune profiles of human pancreatic ductal adenocarcinoma revealed by single-cell mass cytometry
Thomas P Brouwer, Natasja L de Vries, Tamim Abdelaal, Ricki T Krog, Zheng Li, Dina Ruano, Arantza Fariña, Boudewijn P F Lelieveldt, Hans Morreau, Bert A Bonsing, Alexander L Vahrmeijer, Frits Koning, Noel F C C de Miranda

Journal for ImmunoTherapy of Cancer Jul 2022, 10 (7) e004638; DOI: 10.1136/jitc-2022-004638
TGFβ receptor inhibition unleashes interferon-β production by tumor-associated macrophages and enhances radiotherapy efficacy
Pauline Hamon, Marine Gerbé De Thoré, Marion Classe, Nicolas Signolle, Winchygn Liu, Olivia Bawa, Lydia Meziani, Céline Clémenson, Fabien Milliat, Eric Deutsch, Michele Mondini

Journal for ImmunoTherapy of Cancer Mar 2022, 10 (3) e003519; DOI: 10.1136/jitc-2021-003519
PAD-2-mediated citrullination of nucleophosmin provides an effective target for tumor immunotherapy
Ruhul H Choudhury, Peter Symonds, Samantha J Paston, Ian Daniels, Katherine W Cook, Mohamed Gijon, Rachael L Metheringham, Victoria A Brentville, Lindy G Durrant

Journal for ImmunoTherapy of Cancer Feb 2022, 10 (2) e003526; DOI: 10.1136/jitc-2021-003526
Dendritic cell-mediated cross presentation of tumor-derived peptides is biased against plasma membrane proteins
Tim B Fessenden, Lauren E Stopfer, Fiona Chatterjee, Julian Zulueta, Josh Mesfin, Therese Cordero Dumit, Irene Reijers, Esmee P Hoefsmit, Christian Blank, Forest White, Stefani Spranger

Journal for ImmunoTherapy of Cancer Jul 2022, 10 (7) e004159; DOI: 10.1136/jitc-2021-004159
Sensitizing immune unresponsive colorectal cancers to immune checkpoint inhibitors through MAVS overexpression
Bin-Jin Hwang, Li-Chung Tsao, Chaitanya R Acharya, Timothy Trotter, Pankaj Agarwal, Junping Wei, Tao Wang, Xiao-Yi Yang, Gangjun Lei, Takuya Osada, Herbert Kim Lyerly, Michael A Morse, Zachary Conrad Hartman

Journal for ImmunoTherapy of Cancer Mar 2022, 10 (3) e003721; DOI: 10.1136/jitc-2021-003721
Safety and efficacy of nivolumab plus ipilimumab in patients with advanced non-clear cell renal cell carcinoma: results from the phase 3b/4 CheckMate 920 trial
Scott S Tykodi, Lucio N Gordan, Robert S Alter, Edward Arrowsmith, Michael R Harrison, Ivor Percent, Rakesh Singal, Peter Van Veldhuizen, Daniel J George, Thomas Hutson, Joshua Zhang, Jesus Zoco, Jennifer L Johansen, Arash Rezazadeh Kalebasty

Journal for ImmunoTherapy of Cancer Feb 2022, 10 (2) e003844; DOI: 10.1136/jitc-2021-003844

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