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416 Profiling ovarian cancer tumor and microenvironment with disease progression for the design of immunotherapy strategies
Yanruide Li, Christopher Ochoa, Lili Yang

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A465; DOI: 10.1136/jitc-2023-SITC2023.0416
417 Engineer off-the-shelf NKT cells for cancer immunotherapy
Yanruide Li, Lili Yang

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A466; DOI: 10.1136/jitc-2023-SITC2023.0417
418 The development of ‘off-the-shelf’ manufacturing strategies of iPSC-based gamma-delta T cells
Yanjie Li, Lei Ding, Jixue Li, Mariska Ter Haak, Kate Rochlin, Lawrence Lamb

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A467; DOI: 10.1136/jitc-2023-SITC2023.0418
419 Development and mechanism of action of a novel cellular immunotherapeutic platform for the treatment of cancer
Miguel A Lopez-Lago, Vikas Bhardwaj, Xiaoyi Zheng, Pravin Kesarwani, Sagarika Pachhal, Patience Cournoo, Renee Cortez, Charles L Wiseman, William V Williams

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A468; DOI: 10.1136/jitc-2023-SITC2023.0419
420 Insights into the regulation of brain metastasis by natural killer cells
Timothy P McMullen, Aaron J Longworth, Dennis Ma, Isam Adam, Devon A Lawson

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A469; DOI: 10.1136/jitc-2023-SITC2023.0420
421 Integrated analysis of natural killer cell-targeting, first-in-dog clinical trials by single-cell RNA sequencing
Aryana Razmara, Rayna Harris, Lauren Farley, Sean Judge, Marshall Lammers, Cordelia Dunai, William Murphy, Zachary Morris, C Brown, Robert Rebhun, David Vail, Michael Kent, Robert Canter

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A470; DOI: 10.1136/jitc-2023-SITC2023.0421
422 Hijacking upregulated E-selectin while boosting SDF-1α sensing rewires infused NK cells to the AML-perturbed bone marrow
Laura Sanz Ortega, Agneta Andersson, Mattias Carlsten

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A471; DOI: 10.1136/jitc-2023-SITC2023.0422
423 Single cell RNA sequencing reveals functionally validated signatures of cytotoxicity in anti-FRα CoStimulatory Antigen Receptor (CoStAR^TM) activated CD4+ T cells
Katrina Sherbina Baklan, Martina Sykorova, Leyuan Bao, Owen Moon, Robert E Hawkins, Mark Dudley, Gray Kueberuwa, Jinzhou Yuan, John S Bridgeman

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A472; DOI: 10.1136/jitc-2023-SITC2023.0423
424 Adoptive cell therapy with cytokine-induces killer cells armed with immunotools against Her-2 expressing breast cancer
Roberta Sommaggio, Hieu Trong Ngo, Elisa Cappuzzello, Emilia Vigolo, Giulia D’Accardio, Anna Dalla Pietà, Sara Perpinello, Annavera Ventura, Gaia Griguolo, Matthias Peipp, Antonio Rosato

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A473-A474; DOI: 10.1136/jitc-2023-SITC2023.0424
426 Anti-folate receptor alpha (FRα) CoStimulatory Antigen Receptor (CoStAR™) drives distinct cytokine-mediated proliferation responses in CD4+ and CD8+ T cells
Martina Sykorova, Robert E Hawkins, Mark Dudley, Gray Kueberuwa, John S Bridgeman

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A476; DOI: 10.1136/jitc-2023-SITC2023.0426

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