Open access

Deletion of the protein tyrosine phosphatase PTPN22 for adoptive T cell therapy facilitates CTL effector function but promotes T cell exhaustion
Alexandra Rose Teagle, Patricia Castro-Sanchez, Rebecca J Brownlie, Nicola Logan, Simran S Kapoor, David Wright, Robert J Salmond, Rose Zamoyska

Journal for ImmunoTherapy of Cancer Dec 2023, 11 (12) e007614; DOI: 10.1136/jitc-2023-007614
Allogeneic NK cells induce monocyte-to-dendritic cell conversion, control tumor growth, and trigger a pro-inflammatory shift in patient-derived cultures of primary and metastatic colorectal cancer
Elisa C Toffoli, Amanda A van Vliet, Henk W M Verheul, Hans J van der Vliet, Jurriaan Tuynman, Jan Spanholtz, Tanja D de Gruijl

Journal for ImmunoTherapy of Cancer Dec 2023, 11 (12) e007554; DOI: 10.1136/jitc-2023-007554
Caspase-9 inhibition triggers Hsp90-based chemotherapy-mediated tumor intrinsic innate sensing and enhances antitumor immunity
Jingyang Li, Xiaoyu Han, Mayu Sun, Weida Li, Guanghuan Yang, Huiyi Chen, Bao Guo, Jingquan Li, Xiaoguang Li, Hui Wang

Journal for ImmunoTherapy of Cancer Dec 2023, 11 (12) e007625; DOI: 10.1136/jitc-2023-007625
Fibrinogen-like protein 2 promotes tumor immune suppression by regulating cholesterol metabolism in myeloid-derived suppressor cells
Lei Wu, Xudong Liu, Juan Lei, Nan Zhang, Huakan Zhao, Jiangang Zhang, Huan Deng, Yongsheng Li

Journal for ImmunoTherapy of Cancer Dec 2023, 11 (12) e008081; DOI: 10.1136/jitc-2023-008081
iPSC-derived natural killer cells expressing the FcγR fusion CD64/16A can be armed with antibodies for multitumor antigen targeting
Kristin M Snyder, Kate J Dixon, Zachary Davis, Martin Hosking, Geoffrey Hart, Melissa Khaw, Anders Matson, Ryan Bjordahl, Bryan Hancock, Soheila Shirinbak, Jeffrey S Miller, Bahram Valamehr, Jianming Wu, Bruce Walcheck

Journal for ImmunoTherapy of Cancer Dec 2023, 11 (12) e007280; DOI: 10.1136/jitc-2023-007280
Differential requirements for CD4+ T cells in the efficacy of the anti-PD-1+LAG-3 and anti-PD-1+CTLA-4 combinations in melanoma flank and brain metastasis models
Manali S Phadke, Jiannong Li, Zhihua Chen, Paulo C Rodriguez, Jessica K Mandula, Lilit Karapetyan, Peter A Forsyth, Y Ann Chen, Keiran S M Smalley

Journal for ImmunoTherapy of Cancer Dec 2023, 11 (12) e007239; DOI: 10.1136/jitc-2023-007239
Addendum 1: Society for Immunotherapy of Cancer (SITC) clinical practice guideline on immunotherapy for the treatment of hepatocellular carcinoma
Journal for ImmunoTherapy of Cancer Sep 2023, 11 (9) e002794add1; DOI: 10.1136/jitc-2021-002794add1
Lenvatinib plus anti-PD-1 antibodies as conversion therapy for patients with unresectable intermediate-advanced hepatocellular carcinoma: a single-arm, phase II trial
Wenwen Zhang, Shuang Tong, Bingyang Hu, Tao Wan, Haowen Tang, Feilong Zhao, Tianyu Jiao, Junfeng Li, Ze Zhang, Jinping Cai, Huiyi Ye, Zhanbo Wang, Shiqing Chen, Yafei Wang, Xuerui Li, Fangzhou Wang, Junning Cao, Lantian Tian, Xiaochen Zhao, Mingyi Chen, Hongguang Wang, Shouwang Cai, Minggen Hu, Yuezong Bai, Shichun Lu

Journal for ImmunoTherapy of Cancer Sep 2023, 11 (9) e007366; DOI: 10.1136/jitc-2023-007366
Fulvestrant increases the susceptibility of enzalutamide-resistant prostate cancer cells to NK-mediated lysis
Madeline Dahut, Kristen Fousek, Lucas A Horn, Shantel Angstadt, Haiyan Qin, Duane H Hamilton, Jeffrey Schlom, Claudia Palena

Journal for ImmunoTherapy of Cancer Sep 2023, 11 (9) e007386; DOI: 10.1136/jitc-2023-007386
Assessing treatment outcomes of chemoimmunotherapy in extensive-stage small cell lung cancer: an integrated clinical and radiomics approach
Jie Zhao, Yayi He, Xue Yang, Panwen Tian, Liang Zeng, Kun Huang, Jing Zhao, Jiaqi Zhou, Yin Zhu, Qiyuan Wang, Mailin Chen, Wen Li, Yi Gao, Yongchang Zhang, Yang Xia

Journal for ImmunoTherapy of Cancer Sep 2023, 11 (9) e007492; DOI: 10.1136/jitc-2023-007492

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