Open access

Oxazaphosphorines combined with immune checkpoint blockers: dose-dependent tuning between immune and cytotoxic effects
Julia Delahousse, Charles Skarbek, Mélanie Desbois, Jean-Luc Perfettini, Nathalie Chaput, Angelo Paci

Journal for ImmunoTherapy of Cancer Aug 2020, 8 (2) e000916; DOI: 10.1136/jitc-2020-000916
Outcomes and biomarker analyses among patients with COVID-19 treated with interleukin 6 (IL-6) receptor antagonist sarilumab at a single institution in Italy
Vincenzo Montesarchio, Roberto Parrella, Chiara Iommelli, Antonella Bianco, Elio Manzillo, Fiorentino Fraganza, Cristiana Palumbo, Gaetano Rea, Patrizia Murino, Rosanna De Rosa, Luigi Atripaldi, Maurizio D’Abbraccio, Marcello Curvietto, Domenico Mallardo, Egidio Celentano, Antonio Maria Grimaldi, Marco Palla, Claudia Trojaniello, Maria Grazia Vitale, Samuel Lewis Million-Weaver, Paolo Antonio Ascierto

Journal for ImmunoTherapy of Cancer Aug 2020, 8 (2) e001089; DOI: 10.1136/jitc-2020-001089
Antagonistic anti-LILRB1 monoclonal antibody regulates antitumor functions of natural killer cells
Heyu Chen, Yuanzhi Chen, Mi Deng, Samuel John, Xun Gui, Ankit Kansagra, Weina Chen, Jaehyup Kim, Cheryl Lewis, Guojin Wu, Jingjing Xie, Lingbo Zhang, Ryan Huang, Xiaoye Liu, Hisashi Arase, Yang Huang, Hai Yu, Wenxin Luo, Ningshao Xia, Ningyan Zhang, Zhiqiang An, Cheng Cheng Zhang

Journal for ImmunoTherapy of Cancer Aug 2020, 8 (2) e000515; DOI: 10.1136/jitc-2019-000515
Discovery and validation of surface N-glycoproteins in MM cell lines and patient samples uncovers immunotherapy targets
Robyn A A Oldham, Mary L Faber, Theodore R Keppel, Amanda R Buchberger, Matthew Waas, Parameswaran Hari, Rebekah L Gundry, Jeffrey A Medin

Journal for ImmunoTherapy of Cancer Aug 2020, 8 (2) e000915; DOI: 10.1136/jitc-2020-000915
CD163⁺ cytokine-producing cDC2 stimulate intratumoral type 1 T cell responses in HPV16-induced oropharyngeal cancer
Saskia J Santegoets, Chantal L Duurland, Ekaterina J Jordanova, Vanessa J van Ham, Ilina Ehsan, Nikki M Loof, Vipin Narang, Charles A Dutertre, Florent Ginhoux, Sylvia L van Egmond, Marij J P Welters, Sjoerd H van der Burg

Journal for ImmunoTherapy of Cancer Aug 2020, 8 (2) e001053; DOI: 10.1136/jitc-2020-001053
Genetic associations of T cell cancer immune response-related genes with T cell phenotypes and clinical outcomes of early-stage lung cancer
Qinchuan Wang, Jianchun Gu, Linbo Wang, David W Chang, Yuanqing Ye, Maosheng Huang, Jack A Roth, Xifeng Wu

Journal for ImmunoTherapy of Cancer Aug 2020, 8 (2) e000336; DOI: 10.1136/jitc-2019-000336
Rationalized inhibition of mixed lineage kinase 3 and CD70 enhances life span and antitumor efficacy of CD8⁺ T cells
Sandeep Kumar, Sunil Kumar Singh, Navin Viswakarma, Gautam Sondarva, Rakesh Sathish Nair, Periannan Sethupathi, Matthew Dorman, Subhash C Sinha, Kent Hoskins, Gregory Thatcher, Basabi Rana, Ajay Rana

Journal for ImmunoTherapy of Cancer Aug 2020, 8 (2) e000494; DOI: 10.1136/jitc-2019-000494
Combining BRAF inhibition with oncolytic herpes simplex virus enhances the immune-mediated antitumor therapy of BRAF-mutant thyroid cancer
Eva Crespo-Rodriguez, Katharina Bergerhoff, Galabina Bozhanova, Shane Foo, Emmanuel C Patin, Harriet Whittock, Richard Buus, Syed Haider, Gareth Muirhead, Khin Thway, Kate Newbold, Robert S Coffin, Richard G Vile, Dae Kim, Martin McLaughlin, Alan A Melcher, Kevin J Harrington, Malin Pedersen

Journal for ImmunoTherapy of Cancer Aug 2020, 8 (2) e000698; DOI: 10.1136/jitc-2020-000698
Efficacy of immunotherapy in lung cancer with co-occurring mutations in NOTCH and homologous repair genes
Marco Mazzotta, Marco Filetti, Mario Occhipinti, Daniele Marinelli, Stefano Scalera, Irene Terrenato, Francesca Sperati, Matteo Pallocca, Francesco Rizzo, Alain Gelibter, Andrea Botticelli, Giorgia Scafetta, Arianna Di Napoli, Eriseld Krasniqi, Laura Pizzuti, Maddalena Barba, Silvia Carpano, Patrizia Vici, Maurizio Fanciulli, Francesca De Nicola, Ludovica Ciuffreda, Frauke Goeman, Ruggero De Maria, Andrea Vecchione, Raffaele Giusti, Gennaro Ciliberto, Paolo Marchetti, Marcello Maugeri-Saccà

Journal for ImmunoTherapy of Cancer Aug 2020, 8 (2) e000946; DOI: 10.1136/jitc-2020-000946
Correction: MRI of tumor T cell infiltration in response to checkpoint inhibitor therapy
Journal for ImmunoTherapy of Cancer Aug 2020, 8 (2) e000328corr1; DOI: 10.1136/jitc-2019-000328corr1

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