820 MCLA-145 is a bispecific IgG1 antibody that inhibits PD-1/PD-L1 signaling while simultaneously activating CD137 signaling on T cells
Paul Tacken, Liang-chuan Wang, Rinse Klooster, Pieter Fokko Van Loo, Jing Zhou, Arpita Mondal, Yao-Bin Liu, Arjen Kramer, Thomas Condamine, Alla Volgina, Linda Hendriks, Hans van der Maaden, Eric Rovers, Steef Engels, Floris Fransen, Renate den Blanken-Smit, Vanessa Zondag-van der Zande, Abdul Basmeleh, Willem Bartelink, Ashwini Kulkarni, Wilfred Marissen, Cheng-Yen Huang, Leslie Hall, Shane Harvey, Chrysi Kanellopoulou, Shaun Stewart, Horacio Nastri, Lex Bakker, Ton Logtenberg, Simon Plyte, Patrick Mayes, Mark Throsby, Cecile Geuijen
Journal for ImmunoTherapy of Cancer Nov 2020, 8 (Suppl 3) A491; DOI: 10.1136/jitc-2020-SITC2020.0820
