Open access

839 Transcriptomic profiling of T-cell populations in non-muscle invasive and muscle invasive bladder cancer
Viktor Sincic, Milad Abolhalaj, Henrik Lilljebjörn, Alar Aab, Karin Hagerbrand, Peter Ellmark, Thoas Fioretos, Carl Borrebaeck, Fredrik Liedberg, Kristina Lundberg

Journal for ImmunoTherapy of Cancer Nov 2020, 8 (Suppl 3) A501; DOI: 10.1136/jitc-2020-SITC2020.0839
843 Reproducible, MoA-reflecting reporter-based bioassays to enable drug development of biosimilars and biobetters
Jeffrey Nelson, Richard Moravec, Dun Li, Jennifer Wilkinson, Frank Fan, Mei Cong

Journal for ImmunoTherapy of Cancer Nov 2020, 8 (Suppl 3) A502-A503; DOI: 10.1136/jitc-2020-SITC2020.0843
841 CRISPR Cas9 library screen in primary T cells and diffuse large B cell lymphoma cells to identify modulators in tumor-immune interaction
Qian Li, Zhengang Peng

Journal for ImmunoTherapy of Cancer Nov 2020, 8 (Suppl 3) A502; DOI: 10.1136/jitc-2020-SITC2020.0841
842 A novel agonistic anti-CD40 targeting strategy with an affinity peptide binding feature for antigen cargo functionality: improving peptide stability and T cell proliferation
Ida Olsson, Mohamed Eltahir, Sara Mangsbo

Journal for ImmunoTherapy of Cancer Nov 2020, 8 (Suppl 3) A502; DOI: 10.1136/jitc-2020-SITC2020.0842
845 Developing more potent inhibitors of vasoactive intestinal peptide signaling with enhanced efficacy in mouse models of leukemia
Sruthi Ravindranathan, Jian-ming Li, Yiwen Li, Passang Tenzin, Anish Majumdar, Edmund Waller

Journal for ImmunoTherapy of Cancer Nov 2020, 8 (Suppl 3) A503-A504; DOI: 10.1136/jitc-2020-SITC2020.0845
844 Immunomodulatory activity of epigenetic drugs combinations in mesothelioma: laying the ground for new immunotherapeutic strategies
Sara Cannito, Health Biology, Ornella Cutaia, Carolina Fazio, Maria Fortunata Lofiego, Francesca Piazzini, Laura Solmonese, Luana Calabrò, Michele Maio, Alessia Covre

Journal for ImmunoTherapy of Cancer Nov 2020, 8 (Suppl 3) A503; DOI: 10.1136/jitc-2020-SITC2020.0844
846 Neospora caninum – an immunotherapeutic protozoan against solid cancers
Louis Lantier, Agathe Poupee-Beauge, Louis Lantier, Céline Ducournau, Anne Di Tommaso, Stéphanie Germon, Nathalie Moiré, Gordon Lee, Antoine Touze, Isabelle Dimier-Poisson

Journal for ImmunoTherapy of Cancer Nov 2020, 8 (Suppl 3) A504-A505; DOI: 10.1136/jitc-2020-SITC2020.0846
847 Inflammasome activation in M2 macrophage restrain the immune suppressive function
Ronghua Zhang, Tienan Wang, Qing Lin

Journal for ImmunoTherapy of Cancer Nov 2020, 8 (Suppl 3) A505; DOI: 10.1136/jitc-2020-SITC2020.0847
848 Prime-boost vaccination for the treatment of triple negative breast cancer
Seyedeh-Raheleh Niavarani, Christine Lawson, Lee-Hwa Tai

Journal for ImmunoTherapy of Cancer Nov 2020, 8 (Suppl 3) A506; DOI: 10.1136/jitc-2020-SITC2020.0848
849 Optimization of a GM3-containing liposomal vaccine that delivers antigen to CD169+ splenic macrophages
Maarten Nijen Twilhaar, Lucas Czentner Colomo, Joanna Grabowska, Alsya Affandi, Katarina Olesek, Hakan Kalay, Rene van Nostrum, Paul Crocker, Yvette van Kooyk, Gert Storm, Joke den Haan

Journal for ImmunoTherapy of Cancer Nov 2020, 8 (Suppl 3) A506; DOI: 10.1136/jitc-2020-SITC2020.0849

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