Open access

Harnessing radiotherapy-induced NK-cell activity by combining DNA damage–response inhibition and immune checkpoint blockade
Emmanuel C Patin, Magnus T Dillon, Pablo Nenclares, Lorna Grove, Heba Soliman, Isla Leslie, Davina Northcote, Galabina Bozhanova, Eva Crespo-Rodriguez, Holly Baldock, Harriet Whittock, Gabriella Baker, Joan Kyula, Jeane Guevara, Alan A Melcher, James Harper, Hormas Ghadially, Simon Smith, Malin Pedersen, Martin McLaughlin, Kevin J Harrington

Journal for ImmunoTherapy of Cancer Mar 2022, 10 (3) e004306; DOI: 10.1136/jitc-2021-004306
PAD-2-mediated citrullination of nucleophosmin provides an effective target for tumor immunotherapy
Ruhul H Choudhury, Peter Symonds, Samantha J Paston, Ian Daniels, Katherine W Cook, Mohamed Gijon, Rachael L Metheringham, Victoria A Brentville, Lindy G Durrant

Journal for ImmunoTherapy of Cancer Feb 2022, 10 (2) e003526; DOI: 10.1136/jitc-2021-003526
Effect of neoadjuvant chemotherapy on the immune microenvironment in gastric cancer as determined by multiplex immunofluorescence and T cell receptor repertoire analysis
Xiaofang Xing, Jinyao Shi, Yongning Jia, Yunsheng Dou, Zhongwu Li, Bin Dong, Ting Guo, Xiaojing Cheng, Xiaomei Li, Hong Du, Ying Hu, Shuqin Jia, Jian Zhang, Ziyu Li, Jiafu Ji

Journal for ImmunoTherapy of Cancer Mar 2022, 10 (3) e003984; DOI: 10.1136/jitc-2021-003984
Targeting of the alpha_v beta₃ integrin complex by CAR-T cells leads to rapid regression of diffuse intrinsic pontine glioma and glioblastoma
Dustin A Cobb, Jacopo de Rossi, Lixia Liu, Erin An, Daniel W Lee

Journal for ImmunoTherapy of Cancer Feb 2022, 10 (2) e003816; DOI: 10.1136/jitc-2021-003816
Indomethacin-induced oxidative stress enhances death receptor 5 signaling and sensitizes tumor cells to adoptive T-cell therapy
Nada S Aboelella, Caitlin Brandle, Ogacheko Okoko, Md Yeashin Gazi, Zhi-Chun Ding, Hongyan Xu, Gregory Gorman, Roni Bollag, Marco L Davila, Locke J Bryan, David H Munn, Gary A Piazza, Gang Zhou

Journal for ImmunoTherapy of Cancer Jul 2022, 10 (7) e004938; DOI: 10.1136/jitc-2022-004938
Oncolytic peptide LTX-315 induces anti-pancreatic cancer immunity by targeting the ATP11B-PD-L1 axis
Tianyu Tang, Xing Huang, Gang Zhang, Minghao Lu, Zhengtao Hong, Meng Wang, Junming Huang, Xiao Zhi, Tingbo Liang

Journal for ImmunoTherapy of Cancer Mar 2022, 10 (3) e004129; DOI: 10.1136/jitc-2021-004129
Chemical augmentation of mitochondrial electron transport chains tunes T cell activation threshold in tumors
Yosuke Dotsu, Daisuke Muraoka, Naohisa Ogo, Yudai Sonoda, Kiyoshi Yasui, Hiroyuki Yamaguchi, Hideo Yagita, Hiroshi Mukae, Akira Asai, Hiroaki Ikeda

Journal for ImmunoTherapy of Cancer Feb 2022, 10 (2) e003958; DOI: 10.1136/jitc-2021-003958
Rethinking the immunotherapy numbers game
Rebecca A Bekker, Mohammad U Zahid, Jennifer M Binning, Bryan Q Spring, Patrick Hwu, Shari Pilon-Thomas, Heiko Enderling

Journal for ImmunoTherapy of Cancer Jul 2022, 10 (7) e005107; DOI: 10.1136/jitc-2022-005107
Unique characteristics of tertiary lymphoid structures in kidney clear cell carcinoma: prognostic outcome and comparison with bladder cancer
Tsukasa Masuda, Nobuyuki Tanaka, Kimiharu Takamatsu, Kyohei Hakozaki, Ryohei Takahashi, Tadatsugu Anno, Ryohei Kufukihara, Kazunori Shojo, Shuji Mikami, Toshiaki Shinojima, Kazuhiro Kakimi, Tatsuhiko Tsunoda, Eriko Aimono, Hiroshi Nishihara, Ryuichi Mizuno, Mototsugu Oya

Journal for ImmunoTherapy of Cancer Mar 2022, 10 (3) e003883; DOI: 10.1136/jitc-2021-003883
CD19-directed chimeric antigen receptor T cell therapy in Waldenström macroglobulinemia: a preclinical model and initial clinical experience
M Lia Palomba, David Qualls, Sebastien Monette, Shenon Sethi, Ahmet Dogan, Mikhail Roshal, Brigitte Senechal, Xiuyan Wang, Isabelle Rivière, Michel Sadelain, Renier J Brentjens, Jae H Park, Eric L Smith

Journal for ImmunoTherapy of Cancer Feb 2022, 10 (2) e004128; DOI: 10.1136/jitc-2021-004128

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