Open access

Lipid-loaded macrophages as new therapeutic target in cancer
Giulia Marelli, Nicolò Morina, Federica Portale, Marta Pandini, Marta Iovino, Giusy Di Conza, Ping-Chih Ho, Diletta Di Mitri

Journal for ImmunoTherapy of Cancer Jul 2022, 10 (7) e004584; DOI: 10.1136/jitc-2022-004584
ELK3 modulates the antitumor efficacy of natural killer cells against triple negative breast cancer by regulating mitochondrial dynamics
Joo Dong Park, Kwang-Soo Kim, Seung Hee Choi, Gae Hoon Jo, Jin-Ho Choi, Si-Won Park, Eun-Su Ko, Minwook Lee, Dae-Keum Lee, Hye Jung Jang, Sohyun Hwang, Hae-Yun Jung, Kyung-Soon Park

Journal for ImmunoTherapy of Cancer Jul 2022, 10 (7) e004825; DOI: 10.1136/jitc-2022-004825
Immune checkpoint silencing using RNAi-incorporated nanoparticles enhances antitumor immunity and therapeutic efficacy compared with antibody-based approaches
Ji Eun Won, Youngseon Byeon, Tae In Wi, Chan Mi Lee, Ju Hyeong Lee, Tae Heung Kang, Jeong-Won Lee, YoungJoo Lee, Yeong-Min Park, Hee Dong Han

Journal for ImmunoTherapy of Cancer Feb 2022, 10 (2) e003928; DOI: 10.1136/jitc-2021-003928
Delivery of CD47 blocker SIRPα-Fc by CAR-T cells enhances antitumor efficacy
Huanpeng Chen, Yuying Yang, Yuqing Deng, Fengjiao Wei, Qingyu Zhao, Yongqi Liu, Zhonghua Liu, Bolan Yu, Zhaofeng Huang

Journal for ImmunoTherapy of Cancer Feb 2022, 10 (2) e003737; DOI: 10.1136/jitc-2021-003737
Recommendations for standardizing biopsy acquisition and histological assessment of immune checkpoint inhibitor-associated colitis
Christopher Ma, Rish K Pai, David F Schaeffer, Jonathan Krell, Leonardo Guizzetti, Stefanie C McFarlane, John K MacDonald, Won-Tak Choi, Roger M Feakins, Richard Kirsch, Gregory Y Lauwers, Reetesh K Pai, Christophe Rosty, Amitabh Srivastava, Joanna C. Walsh, Brian G Feagan, Vipul Jairath

Journal for ImmunoTherapy of Cancer Mar 2022, 10 (3) e004560; DOI: 10.1136/jitc-2022-004560
Soluble PD-L1 as an early marker of progressive disease on nivolumab
Kathleen M Mahoney, Petra Ross-Macdonald, Long Yuan, Linan Song, Eliseo Veras, Megan Wind-Rotolo, David F McDermott, F Stephen Hodi, Toni K Choueiri, Gordon J Freeman

Journal for ImmunoTherapy of Cancer Feb 2022, 10 (2) e003527; DOI: 10.1136/jitc-2021-003527
Natural high-avidity T-cell receptor efficiently mediates regression of cancer/testis antigen 83 positive common solid cancers
Qingyang Li, Wei Hu, Baoyi Liao, Chanchan Song, Liangping Li

Journal for ImmunoTherapy of Cancer Jul 2022, 10 (7) e004713; DOI: 10.1136/jitc-2022-004713
DNA methylation profiles differ in responders versus non-responders to anti-PD-1 immune checkpoint inhibitors in patients with advanced and metastatic head and neck squamous cell carcinoma
Angelika Martina Starzer, Gerwin Heller, Erwin Tomasich, Thomas Melchardt, Katharina Feldmann, Teresa Hatziioannou, Stefan Traint, Christoph Minichsdorfer, Ursula Schwarz-Nemec, Maja Nackenhorst, Leonhard Müllauer, Matthias Preusser, Anna Sophie Berghoff, Thorsten Fuereder

Journal for ImmunoTherapy of Cancer Mar 2022, 10 (3) e003420; DOI: 10.1136/jitc-2021-003420
Neoantigen vaccine-induced CD4 T cells confer protective immunity in a mouse model of multiple myeloma through activation of CD8 T cells against non-vaccine, tumor-associated antigens
Selma Bekri, Reunet Rodney-Sandy, Diana Gruenstein, Anna Mei, Bjarne Bogen, John Castle, Daniel Levey, Hearn Jay Cho

Journal for ImmunoTherapy of Cancer Feb 2022, 10 (2) e003572; DOI: 10.1136/jitc-2021-003572
Clinical efficacy of atezolizumab plus bevacizumab and chemotherapy in KRAS-mutated non-small cell lung cancer with STK11, KEAP1, or TP53 comutations: subgroup results from the phase III IMpower150 trial
Howard Jack West, Mark McCleland, Federico Cappuzzo, Martin Reck, Tony SK Mok, Robert M Jotte, Makoto Nishio, Eugene Kim, Stefanie Morris, Wei Zou, David Shames, Meghna Das Thakur, Geetha Shankar, Mark A Socinski

Journal for ImmunoTherapy of Cancer Feb 2022, 10 (2) e003027; DOI: 10.1136/jitc-2021-003027

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