Open access

889 IFN-γ modulated DCsion making on T-cell anti-tumor immunity
Tzu-Hsuan Chang, Francesca Alfei, Ping-Chih Ho

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A990; DOI: 10.1136/jitc-2023-SITC2023.0889
890 Nivolumab plus ipilimumab in anti-PD(L)-1 naïve and experienced HCC patients — single institute experience in Taiwan
Nai-Jung Chiang, Ming-Huang Chen, San-chi Chen

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A991; DOI: 10.1136/jitc-2023-SITC2023.0890
891 Beta-adrenergic blockade licenses the use of immunotherapy in primary and metastatic brain tumors
Selena J Lorrey, Lucas P Wachsmuth, Jessica Waibl Polania, Alexandra Hoyt-Miggelbrink, John Finlay, Mackenzie Price, Corey Neff, Xiuyu Cui, Emily Lerner, Daniel Wilkinson, Kelly Hotchkiss, Ethan Srinivasan, Quinn T Ostrom, Peter E Fecci

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A992; DOI: 10.1136/jitc-2023-SITC2023.0891
892 Non-redundant mechanisms of resistance to immunotherapy and radiotherapy converge on innate immunity
Anthony T Nguyen, Tahir B Dar, Jolene Viramontes, Satchel Stevens, Julie Jang, Emily Ko, Eric M Chung, Samuel Zhang, Katelyn M Atkins, Mitchell Kamrava, Howard M Sandler, Jlenia Guarnerio, Simon Knott, Zachary Zumsteg, David M Underhill, Stephen L Shiao

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A993; DOI: 10.1136/jitc-2023-SITC2023.0892
893 A systematic review of predictive biomarkers for immunotherapy in non-small cell lung cancer (NSCLC)
Judith Pérez Granado, Darren Gonzalez, Kinisha Gala, Ankit Kalucha, Bruno Larvol, Mark Gramling

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A994; DOI: 10.1136/jitc-2023-SITC2023.0893
894 Conserved immune inhibitory receptor-signaling in macrophages limits antitumour chemo-immunotherapy
Isaure Vanmeerbeek, Stefan Naulaerts, Jenny Sprooten, Raquel Salvador, Jannes Govaerts, Rosa Trotta, Samantha Pretto, Shikang Zhao, Sarah Trusso Cafarello, Joren Verelst, Maarten Jacquemyn, Martyna Pociupany, Louis Boon, Susan M Schlenner, Sabine Tejpar, Dirk Daelemans, Massimiliano Mazzone, Abhishek D Garg

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A995; DOI: 10.1136/jitc-2023-SITC2023.0894
895 Immunosuppressive signaling is activated in enzalutamide resistant prostate cancer
Pengfei Xu, Joy C Yang, Bo Chen, Christopher Nip, Leyi Wang, Jonathan EVan Dyke, Christopher P Evans, William Murphy, Chengfei Liu

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A996; DOI: 10.1136/jitc-2023-SITC2023.0895
896 Characterizing macrophage heterogeneity in HR+/HER2- metastatic breast cancer reveals novel mechanisms of resistance
Kelly F Zheng, Kenichi Shimada, Madeline G Townsend, Tianyu Li, Nabihah Tayob, Molly DiLullo, Eileen Wrabel, Elizabeth A Mittendorf, Tanya Keenan, Romualdo Barroso-Sousa, Sandro Santagata, Sara M Tolaney, Peter K Sorger, Jennifer L Guerriero

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A997-A998; DOI: 10.1136/jitc-2023-SITC2023.0896
897 AST-301, a pDNA-based cancer vaccine encoding HER2-ICD, enhances anti-tumor effect of HER2-ADC in a HER2-expressed gastric cancer xenograft model
JinHo Kang, Hyo-Hyun Park, Jee Hyun Choi, Jinback Lim, Seong-Yong Jang, Min-Ah Kim, Myeong-Kyu Park, Yun-Hee Park, Soyeon Lim, Chul-Woong Chung, Jin Kyeong Choi, Eunkyo Joung, Hun Jung

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A999; DOI: 10.1136/jitc-2023-SITC2023.0897
638 Characterisation of the immune response to EO2401, a new immunotherapy approach against cancer, plus nivolumab in recurrent glioblastoma: The EOGBM1–18/ROSALIE study
Ana Maia, Hélène Toussaint, Joao Gamelas Magalhaes, Ahmed Idbaih, Maria Vieito Villar, Ghazaleh Tabatabai, Agostina Stradella, Francois Ghiringhelli, Michael C Burger, Iris Mildenberger, Ulrich Herrlinger, Macarena González, Alice Hervieu, Marta GilMartin, Mirjam Renovanz, Mehdi Touat, Patrick Wen, Antje Wick, Christophe Bonny, Jean-Michel Paillarse, David Reardon, Wolfgang Wick, Cécile Gouttefangeas

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A730; DOI: 10.1136/jitc-2023-SITC2023.0638

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